Answer / bujji kanchi

1)inject same concentration of impurity and active

Ratio of impurity area and active area

correct the concentrations.


Best practice is

Inject LOQ to 150% of specification around 5 levels

and calculate the slope of impurity and slope of active

take the slpe ratio.



Regards,
Bujji Kanchi.

Answer / javed

RRF Can be calculated by comparing the area of standard with
area of impurity x conc of imp by conc of std x 100.

The colour presence in kmno4 is due to.

1 Answers   Laurus,

---

how to develop the shorter run time for pharmacopeial methods having 100 min run time?

3 Answers   Reddy Labs,

---

What id the resolution factor

1 Answers  

---

How to use RF and rrf in Rs calculation( either multiply or divide)?

4 Answers   Micro Labs,

---

is there any exact definition for Theoritical plates ? chennu srinivas

5 Answers  

---

what is defferance between dipolemoment and polarity

1 Answers   Neuland,

---

what is LC - MS ? What its wide use in cro/pharmaceutical Industry

4 Answers   Ranbaxy,

---

how do u optimise hplc method

1 Answers  

---

I have 1 gram of Diphenylamine and want to make a 10,000 or 1000 ppm solution in methanol. How do I make this?

9 Answers   Midas Technologies,

---

How to calculate the maximum loaded sample concentration in HPLC column?

2 Answers  

---

How can we determine Moisture content of HI?

1 Answers   Cipla, Reddy Labs,

---

How we get DST moisture 15.4-16.0%. what is the calculation or method behind it.

2 Answers  

---