HOW RRF IS CALCULATED IN HPLC

Answer Posted / javed

RRF Can be calculated by comparing the area of standard with
area of impurity x conc of imp by conc of std x 100.

Is This Answer Correct ?    9 Yes 8 No



Post New Answer       View All Answers


Please Help Members By Posting Answers For Below Questions

We use hicrome 10 cxs column in hplc analysis....pls tell me.. what is the meaning of 10 cxs?

1162


Which products will produce when acetic anhydride reacts with Ter-butanol, Sec-butanol, Iso butanol, Dimethylamine etc.

2397


What is gelatinization?

1182


how decide the clining method and cleaning method validation require for this perticular products?

308


what is procedure of actual procedure for registration of drug?

1461






all types of questions asked at the cipla interview

4139


In HPLC calibration, caffeine is used as primary standard for wave length calibration due to caffeine is having dual maxima at 273 & 205 nm and one minima at 245 nm. Any body can give reference of these details from any pharmacopeia (with chapter no.) or any other authentic guideline?

1462


how to selecet an exact coloumn for an new molecule development by hplc how to select exact salt as buffer for new molecule development by hplc what is the the process to select the mode of saparation of compoundes by hplc what is the use of ph of buffer what is use of buffer,ph,organic phase,ans methods how the molecules get saparated in coloumn,

2046


what is classification of elemental impurities? what is risk assement in elemental impurities?

345


using gradient pressure in gas chromatography are not ?using gradient pressure why

2943


If change in specification which parameter require to do for validation? if change in chromtographic condition then which parameter? if api change then which parameter? if change composition then which parameter? if old method not work out then whicj parameter? if additional one impurity added then which parameter of validation require to do on above each conditions? elaborate separately

362


Identify problem faced when mass spectroscopy is used with HPLC system ?

1387


Please give idea about method development for cleaning method and how maco level establish

278


While performing TOC sst analysis Zero shift disabled & sample analysis zero shift enabled why?

2357


How we performed the force degradation for drug substance, is any specific guideline is available for each parameter(Acidic, basic, oxidation,heat)? what conditions you mentained for above parameters.

1801