Answer Posted / bujji kanchi
1)inject same concentration of impurity and active
Ratio of impurity area and active area
correct the concentrations.
Best practice is
Inject LOQ to 150% of specification around 5 levels
and calculate the slope of impurity and slope of active
take the slpe ratio.
Regards,
Bujji Kanchi.
| Is This Answer Correct ? | 8 Yes | 0 No |
Post New Answer View All Answers
How to choose the which salt is suitable for mobilephase
what is mean by ambient temperature?
Tell me something about Vitamin A test method by HPLC
what is the acceptance criteria for enteric coated tablets in 0.1n hcl validation in each parameter?
Which is the highly polar and highly non polar column in HPLC?
How will u perform degradation study in detectors other thann PDA in HPLC Methodology
what is partion and column chromatography
if your product is soluble in 0.1n hcl and water then which you choose as media from these 2 media?
what is the procedure for cleaning of lenses of hatr accesory of ftir instrument?
WHAT IS THE PARAMETER FOR THE SELECTION OF MOBILE PHASE IN HPLC?
if instrument calibration fails then what require to do?
What is delay volume?
if you get peak in blank then what require to do?
why multimedia dissolution require to do?