Answer / anil

These are generally used in the Related Substances(RS) analysis By HPLC.
RT Is the "Retention Time" & RRT is the Relative retention Time.
RRT = 1/RT

Answer / pavana

RT-Retention time (RT) is a measure of the time taken for a solute to pass through a chromatography column. It is calculated as the time from injection to detection. The RT for a compound is not fixed as many factors can influence it even if the same GC and column are used.
RRT-Relative Retention time. relative retention time - ratio between the net retention time of a substance and that of a standard compound. residual silanols - the silanol (-Si-OH) groups that remain on the surface of a silica after a modifier ligands is chemically bonded onto its surface.

how to calculate elemental impurities?

0 Answers  

---

What are the concentration limit for class-1 residual solvents in ICH ?

1 Answers   Lupin,

---

In Analytical method development related substance method when did follow w/w method when did follow area normalisation method

2 Answers   Dr Reddys, Sun Pharma,

---

what is the importance of peak purity in HPLC and how we can calculate through manul(not software)?

0 Answers   Neuland,

---

how calibrate the hplc detector

2 Answers   Cipla, Shraddha Analytical Services,

---

What is Temperature ?

2 Answers   Reddy Labs,

---

what are the basic requirement for the WHO audit?

1 Answers   BioPlus,

---

UV and PDA detector, which have less signal to noise ratio?

0 Answers  

---

According to ICH,India is coming under which climatic zones?

1 Answers   Cipla,

---

why we are doing seal wash and needle wash?

3 Answers  

---

what is the defferance between the potency and working standard

1 Answers   Arbro Pharmaceuticals, Caplin Point, ECOlogics, Matrix, Orchid, Venus Remedies,

---

how to prepare working standard in our laboratory aganist reference standard ?

4 Answers   Merit Biolabs, Unichem,

---