Retention time & Relative Retention time Definition &
between difference?
How to Calculate response factor(RF) & relative response
factor(RRF)?
Answers were Sorted based on User's Feedback
Rt is identified main peak.
but rrt is identified impurities purpose
rt*rrt-impurities rt is identified
Is This Answer Correct ? | 11 Yes | 3 No |
Answer / gangadhar n v
RT is the retention time of Analyte or Impurity.
RRT is the ratio between the Impurity Retention time to Analyte Retention time.
RF means Response Factor.It is the ration between the Impurity Concentration to Impurity Area.
RRF means Releative Response Factor.It is equals to 1/RF. or Slope of the Impurity/Slope of the Analyte.It is findout from the Linearity Curve.RF is Called as Correction Factor.
Is This Answer Correct ? | 9 Yes | 4 No |
Answer / aruna
rt is a respective compound retention time, rrt means imp rt/main peak rt.
Response factor like rt, rrf means slop of imp/slope of the api, through linearity curve we find out the rrf.
Is This Answer Correct ? | 8 Yes | 4 No |
Home heating oil or furnace oil what is made from? Can (base oil plus diesel/kerosen) = home heating oil?
How much sample concentration should i inject against diluted standard in related substances for drug product in hplc analysis
what is the difference between polarimeter lamp and ir lamp
how to convert normal phase hplc to reverse phase and vice versa?
if the flow rate is increases then any changes in retention time in hplc
Which is the best mobile phase to separate organic acids using C8 column. And how should the samples be prepared for hplc?
what is the difference between capillary and glass column in GC
why results are variation in same samples analysis in gc and hplc ?
2. Two grams of Benzoic acid are dissolved in 200 ml of water and extracted with 200 ml of diethyl ether. The distribution coefficient of benzoic acid is 100, and its dissociation constant is 6.5 10-5. Calculate the distribution ratio (D) of benzoic acid at pH 2, 5, and 6. 3. Calculate D at pH 2 to 10 (1 unit apart) in the above problem, and plot D versus pH.
How NMR spectra can be calibrated in presence or absence of TMS?
what is analytical chemistry all about?
What is difference between chemical Assay and Hplc assay?