What is the difference between STANDARDIZATION and CALIBRATION of instrument like KF? why do we standardization of KF everyday? Why the KF factor being only 5.02 etc?
Answers were Sorted based on User's Feedback
Answer / ravindra reddy
calibration means whether instruments working properly or not where as standerdisation means finding the exact strength value of concered solution
| Is This Answer Correct ? | 41 Yes | 5 No |
Calibration is related to instrument
Stantardisation is related to the solution
In calibration we check the instrument performance wether working or not by using the standards
1 ml of kf reagent is required to neutralise 5 mg of water so the kf strength is near 5 mg/ml
Actually the kf reagent consist of so2 and I so I present in kf is not stable so we need to check the solution strength daily morning or when ever kf solution is changed
| Is This Answer Correct ? | 19 Yes | 2 No |
Answer / naseem khan
Yeah It should be cleared that we do Standardization of Solution and We calibrate to instrument not any Chemical solution.
We find out the unknown concentration of solution by using the known concentration solution, The exact strength of the solution.
Through the calibration we find out whether the perticuler instrument working properly or not to any specific test.
| Is This Answer Correct ? | 5 Yes | 0 No |
Answer / geethanath
The KF solution contains Iodine. Which will liberate from the solution. So When Iodine is liberate from the solution the strength of the solution will dicrease. One molicule of iodine will react to one molecule of water. For determining the Iodine strength we have to standardise.
Calibration is a periodic review point to check whether the instrument is working properly or not.
KF factor shold not be equal 5 at every time. The molarity may differ for hygroscopic materils. The diluted KF is having 2.5 as a factor.
| Is This Answer Correct ? | 2 Yes | 0 No |
Answer / falguni patel
1ml of KF reagent consumes 5mg of water minimum....so its factor is near 5.
You can see this relation on KF reagent bottle.
| Is This Answer Correct ? | 0 Yes | 4 No |
why urasil use in hplc column perfomance?
why we inject sample TWICE in ASSAY by HPLC analysis but in RS once?
4 Answers Aurobindo, DRL, Neuland,
what is turbidimetric titration?Give 2 examples.
What is the Column Endcaping in HPLC ?
How to standardization of 1N H2SO4?
Suppose we prepared pH buffer solution in lab.and calibrate against NIST solution, and same shall going to used upto 30 days. is it possible to stable pH and apperance ? suggest ?
what are the normalisation, internal standard and external standerd methods in HPLC.
How to now that my acid is contact with base or base is contact with acid in drugs, is there any techniq to identify the formation of salt(drug)
Give me details about dissolution , with name ?
How you can calculate pKa ?
Which std. used for standrdisation of ZnSO4?
What is the difference between the optics of UV and PDA Detectors ?