How you can calculate pKa ?
Answers were Sorted based on User's Feedback
Answer / s rampal
-log10[Ka] =pKa where Ka is dissociation constant and can
be calculated by using formula Ka = [H+][B-]/[HB]
Is This Answer Correct ? | 27 Yes | 1 No |
Answer / pratap rasam
Carry out acid-base titration and note down the
readings.Plot a graph of pH nersus volume of titrant added.
Locate the equivalence point. Compute the volume exactly
half the equivalent point and from this volume
corresponding pH is nothing but pKa.
Is This Answer Correct ? | 12 Yes | 1 No |
The equation for pKa is this:
Presuppose you have a compound HX is
HX --> H+ + X-
pKa = -log Ka
To find the Ka:
Ka = [H+] x [X-]/[HX]
Ka (is dissociation constant) is always products over
reactants.
Is This Answer Correct ? | 3 Yes | 0 No |
Answer / sachin.bedwal
pKa = pH-iog(conjugate base)/conjugate acid).
Is This Answer Correct ? | 3 Yes | 2 No |
Answer / ganesh bhavar
FOR PKa DTETERMINATION DIFFERENT METHOD USED AS FOLLOWS
1.SPECTROSCOPY METHOD
2. POTENTIOMETRIC METHOD
3. CAPILLARY CHROMATOGRAPHIC METHOD
Is This Answer Correct ? | 4 Yes | 3 No |
How much area of methanol or other solvent are acceptable in blank (Diluent) of Gas chromatography.
What is the diff b/n OVI and Residual solvents
why required specificity in valdation
what is titrent,& titrate
2 Answers Graviti Pharmaceuticals,
Why pH range is maximum 14.0
What is FDA form 482c?
what is the origin to prepare standard operating procedure
control of resolution in calibration of IR
mode of absorption in alimentary canal?
how to start the method development of Dissolution and related substances.
Is it necessary to inject three replicate for accuracy in AMV.
How to define samples weight in moisture content