how to regulate noise in HPLC?
Answers were Sorted based on User's Feedback
Answer / santosh
Don't select wavelength nearer to cutoff of mobile phase or prepare mobile phase transpersonal to selected wavelength
| Is This Answer Correct ? | 3 Yes | 0 No |
Answer / a.iyyappan
Baseline noise can be regulated by using HPLC grade solvents and high purity buffer salts.
Detector wavelength should be follow UV CUTT OFF POINT.
| Is This Answer Correct ? | 2 Yes | 0 No |
what is impurity profile. how to interpret this impurity profile to a drug product or drug substance.
what is the cleaning validation?
why salicylic acid not use for dissolution.
2 Answers Cipla, Indo Baijin Chemicals,
Why we are performing wavelength accuracy at lower and higher wavelengths in HPLC calibration
Dear Sir, This is Thirunavukkarasu am working in Ordain Health Care AR&D, Am Having one problem While doing method development my question Metadoxine and Pyridoxine same chemical nature and structural activity i tried lot of methods but Analyte eluted same Retantion time i cant separate both peaks. solubility, pH both are same only only difference melting point metadoxine 210 C Pyridoxine 102 C please do the help needful for me
what is mean by assay?
for which product require to do content uniformity? what is limit of cu?
Why base line not start from zero in GC Chromatography analysis.
What is the formula for relative diffrence for standard solution in solution stability in validation?
what is lod and loq ?,why use k2cr2o7 , kcl h2so4 in uv calibration ?,why use benzophenone & caffene acetone in hplc calibration ?,what is leading peak in hplc ?why we do the calibration of limit of stry light in hplc & uv ?
what is mean by nitrosamine impurities?
What are the factors effect peak shape in HPLC ?
2 Answers College School Exams Tests,