IF THE COMPOUND PKA IS 5.3 WHY WE ARE ADJUSTING PH+/-2 OF
THE COMPOUNDS PKA. WHAT IS THE CONDITION
Answers were Sorted based on User's Feedback
pKa=pH+log [un ionised]/[ionised]
at the half neutralisation point
un ionised concentration= ionised concentration
so pKa=pH+log1
pKa=pH because log1=0
if we didnt adjudt pH +/-2.0 we may get peak split because
for un ionised we get one peak and ionised we get one more
peak
| Is This Answer Correct ? | 3 Yes | 1 No |
pKa=pH+log [un ionised]/[ionised]
at the half neutralisation point
un ionised concentration= ionised concentration
so pKa=pH+log1
pKa=pH because log1=0
if we didnt adjudt pH +/-2.0 we may get peak split because
for un ionised we get one peak and ionised we get one more
peak
| Is This Answer Correct ? | 1 Yes | 2 No |
why use k2cr2o7 , kcl h2so4 in uv calibration
Why sodium hydroxide used for maintain pH of phosphate buffer
what is role of pH in mobile phase
3 Answers Cipla, Dhanuka Laboratories,
What is the difference between high pressure gradient and low pressure gradient in hplc?
Why methanol & acetonitrile is mostly used for hplc analysis?
Why to use propyl paraben in HPLC gradient calibration
what is definition of validation? which components are followed give detail?
give me method of calculating co relation of coefficient for HPLC,SOR & ANY OTHER
How you will select the runtime in HPLC for a drug in method development.
6 Answers Aurobindo, GVK, Lesanto Laboratories,
What is difference between Primary and secodary reference standard?
what is partion and column chromatography
what is the difference between Tailing Factor & Asymmetry
8 Answers Ashish Life Science, BEC Chemicals, Jubilant,