Interested to Buy Any Domain ? << Click Here >> for more details...
IF THE COMPOUND PKA IS 5.3 WHY WE ARE ADJUSTING PH+/-2 OF
THE COMPOUNDS PKA. WHAT IS THE CONDITION
- 2 Answers
- 10414 Views
- Dr Reddys, Reddy Labs, I also Faced
- E-Mail Answers
Answer Posted / ramya sarma
pKa=pH+log [un ionised]/[ionised]
at the half neutralisation point
un ionised concentration= ionised concentration
so pKa=pH+log1
pKa=pH because log1=0
if we didnt adjudt pH +/-2.0 we may get peak split because
for un ionised we get one peak and ionised we get one more
peak
| Is This Answer Correct ? | 1 Yes | 2 No |
Post New Answer View All Answers
What is similarity factor?
In HPLC Calibration, On which basis RSD Limit of noise test is fixed (NMT 33.0 % )
What is the Formula for coreletion coefficient in plhplc calibration
why sre you used Potassium hydrogen phthalate in standarisation of 1N NaOH and 0.1 N Perchloric Acid?
How to determine water content of bis tetrazole amine mono ammonium salt
How will u perform degradation study in detectors other thann PDA in HPLC Methodology
what is the purge flow & how to calculate
what is turbidimetric titration?Give 2 examples.
why require the ph, buffer during hplc mobile phase?
for which product require to do content uniformity? what is limit of cu?
What are the primary considerations in extractables and Leachables ?
How do we fix the sample concentaryion in hplc method development. What is the basis?
if you have given one product then how you determine the impurity in that?
what is the disso medium for tropsiun chloride
when we talk about change in entropy we consider total entropy means of surround +entropy of system but when we talk about change in Gibss free energy we consider entropy of system.explain with reason.
