ramya


{ City } hyderabad
< Country > india
* Profession * research associate
User No # 69398
Total Questions Posted # 0
Total Answers Posted # 3

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Questions / { ramya }
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Answers / { ramya }

Question { Dr Reddys, 9633 }

IF THE COMPOUND PKA IS 5.3 WHY WE ARE ADJUSTING PH+/-2 OF
THE COMPOUNDS PKA. WHAT IS THE CONDITION


Answer

pKa=pH+log [un ionised]/[ionised]
at the half neutralisation point
un ionised concentration= ionised concentration

so pKa=pH+log1
pKa=pH because log1=0

if we didnt adjudt pH +/-2.0 we may get peak split because
for un ionised we get one peak and ionised we get one more
peak

Is This Answer Correct ?    3 Yes 1 No

Question { Dr Reddys, 9633 }

IF THE COMPOUND PKA IS 5.3 WHY WE ARE ADJUSTING PH+/-2 OF
THE COMPOUNDS PKA. WHAT IS THE CONDITION


Answer

pKa=pH+log [un ionised]/[ionised]
at the half neutralisation point
un ionised concentration= ionised concentration

so pKa=pH+log1
pKa=pH because log1=0

if we didnt adjudt pH +/-2.0 we may get peak split because
for un ionised we get one peak and ionised we get one more
peak

Is This Answer Correct ?    1 Yes 2 No


Question { 16166 }

why IR graph or spectra comes down ? Any reason


Answer

In HPLC we are taking absorbance on Y-AXIS in IR we are
taking transmittance on Y-axis, absorbance is inversly
proportional to transmittance so IR Spectra comes down

Is This Answer Correct ?    18 Yes 0 No