Interested to Buy Any Domain ? << Click Here >> for more details...
what is the difference between Tailing Factor & Asymmetry
- 8 Answers
- 53477 Views
- Ashish Life Science, BEC Chemicals, Jubilant, I also Faced
- E-Mail Answers
Answers were Sorted based on User's Feedback
Answer / m
Tailing Factor: is shows u r Tailing of peak eqation is T =
W0.05/2f
Assaymetry : is shows u r symmetry of peak equation is As =
ab/bc means fornting/tailing
| Is This Answer Correct ? | 47 Yes | 6 No |
Answer / saji
Asymmetry
A factor describing the shape of a chromatographic peak.
Theory assumes a Gaussian shape peak that is symmetrical.
The peak asymmetry factor is the ratio (at 10 percent of
the peak height) of the distance between the peak apex and
the back side of the chromatographic curve to the distance
between the peak apex and the front side of the
chromatographic curve. A value >1 is a tailing peak, while
a value <1 is a fronting peak.
Tailing
A peak with an asymmetrical factor of >1. An asymmetrical
peak is the result of a component that is excessively
retarded in eluting. Tailing is caused by sites on the
packing that have a stronger than normal retention for the
solute. A typical example of a tailing phenomenon is the
strong adsorption of amines on the residual silanol groups
of a low coverage reversed-phase packing.
| Is This Answer Correct ? | 24 Yes | 3 No |
Answer / anuj grewal
Tailing Factor is same the symmetry factor and calculate by the formula
T= W/2A
Where,
W- width of peak at 5%
A- distance of front edge from center at 5%
Asymmetry is the unsimilarity of peak and calculate by the formula
As = BC/AB
Where,
BC- Distance of back edge from center at 10% height
AB- Distance of front edge from center at 10% height.
| Is This Answer Correct ? | 12 Yes | 2 No |
asymmetry factor=1
If asymmetry factor greater than one then that peak is Tailing
If asymmetry factor less than one then that peak is fronting
| Is This Answer Correct ? | 1 Yes | 3 No |
Answer / pankaj deshmukh
The tailing factor is determined by drawing a perpendicular line from the peak centre to the baseline of the peak. Then the peak width and the front half-width are measured for the peak at 5% of the height of the peak. The tailing factor is simply the entire peak width divided by twice the front half-width while asymmetry factor measured at 10% of the peak height. The asymmetry factor is determined by dividing the back half-width by the front half-width
| Is This Answer Correct ? | 1 Yes | 4 No |
Answer / srj
Both are same but, Asymmetry is qualitative and tailing is qualitative as well as quantitative.
e.g.
1) Asymmetry ( Peak is symmetric or asymmetric)
2) Tailing factor ( If asymmetry factor greater than one then that peak is Tailing, If asymmetry factor less than one then that peak is fronting)
In tailing factor u can tell ur peak is symmetric or not( if not the how much ur peak is not symmentic)
| Is This Answer Correct ? | 0 Yes | 5 No |
Answer / a.s.r 123
BOTH ARE SAME THE LIMIT IS MAXIMUM 2 MINIMUM 0.8 ACCORDING TO USP
| Is This Answer Correct ? | 5 Yes | 24 No |
What is a difference between potency and purity?
my name is santhosh i cmpleted b.pharmacy in 2009 then i went to uk in 2010 to pg diploma business management. after i came back to india.. recently again apply to uk for pharmaceutical analysis. they refused my visa you failed to explain y u r change subject. so plz ineed answer for y change the cource
What is diffrence between extractable volume and deliverable volume? Answer pls
Can we interpret accuracy from linearity in method validation?
why using factor 1.00639 in burette calibration of kf
difference between selectivity and specificity
2 Answers Troikaa Pharmaceuticals,
give me method of calculating co relation of coefficient for HPLC,SOR & ANY OTHER
Which is the best mobile phase to separate organic acids using C8 column. And how should the samples be prepared for hplc?
why multimedia dissolution require to do?
what is difference between GC & GC-HS
What are the tests used in Hplc?Name any two.
what is the effect of injection volume calculate flow rate in perkin elmer headspace? (ccm parameter in HS)
Organic Chemistry 
