Interested to Buy Any Domain ? << Click Here >> for more details...
what r the reasons to get peak telling?
- 6 Answers
- 16240 Views
- Cipla, I also Faced
- E-Mail Answers
Answers were Sorted based on User's Feedback
Answer / ravi kumar
due to the presence of residual silanols on the reverse
phase column which interacts with acids or bases (mostly
bases)cause them to tail
| Is This Answer Correct ? | 19 Yes | 1 No |
Answer / nageswar rao
the following parametrs are reasons
1.silinol interaction of basic amines
2.adsorption of acidic compounds
3.mass overloaded
4.injecting sample in worng solvent significantly stroger
than mobile phase
| Is This Answer Correct ? | 15 Yes | 1 No |
Answer / nagesh.v@sai advantium.com
Due to column efficiency Decreaced
| Is This Answer Correct ? | 11 Yes | 2 No |
Answer / subash
The following reasons are causes of peak tailing
1.Injecting the sample in a solvent significantly stroger
than the mobile phase
2.Interaction of stationary phase silanols with basic
analyte
3.Adsorption of acidic compounds on the stationary phase
4.Sample mass overloaded
5.A void in the column packing bed
| Is This Answer Correct ? | 5 Yes | 0 No |
Answer / t.venkata reddy
below reasons causes peak tailing
1)Analytical column contaminated
2)Mobile phase contamination/deterioation
3)unswept dead volume
4)basic substance-silanol interation.
| Is This Answer Correct ? | 2 Yes | 0 No |
Answer / palabindela
column over loaded or high injection volume
| Is This Answer Correct ? | 0 Yes | 2 No |
what is definition of validation? which components are followed give detail?
What is difference between Potency & purity
How to set analytical specification for combination products?
Shall i use a same hplc column for two different products.?
What is pooled sample in Dissolution
2 Answers Graviti Pharmaceuticals, Lupin,
WHAT IS THE USAGE OF REFRACTIVE INDEX IN PHARME FIELD
what is defferance between dipolemoment and polarity
What are the parameters for the method development of Gas Chromatography and GC-HS?
what is the importence and role of LCMS and LCMS/MS and their applications? which type of compounds are analysis by lcms?
Which parameters require to do in tech transfer?
Weight balance variation limit during analysis
7 Answers Amneal Pharmaceuticals,
If we have 120 minutes run time method for HPLC and you wan to decrease the Run time so what should you do??
Organic Chemistry 
