Interested to Buy Any Domain ? << Click Here >> for more details...
what is the difference between M.C and LOD
- 21 Answers
- 72846 Views
- Aurobindo, Cipla, Laurus, Matrix, Synthokem Labs, I also Faced
- E-Mail Answers
Answers were Sorted based on User's Feedback
Answer / aditya
Hi to all
By using M.C We can measure Moisture Present in our drug
By using LOD we can determine only Class-3 Solvents according ICH Q3C_R5 besides moisture content..
Only Class 3 solvents are likely to be present. Loss on drying is less than 0.5%.
If it is wrong please let me know right one
Than Q
| Is This Answer Correct ? | 2 Yes | 0 No |
by m.c. we have to found out only water content present in the sample
while lod we have to find out water content and any solvents{non volatile}present in the sample
| Is This Answer Correct ? | 1 Yes | 0 No |
mc :onely water content identificaton
lod:water & solvents identificaton
| Is This Answer Correct ? | 1 Yes | 0 No |
Answer / md. prince bpharm
Moisture content = Intramolecular water + Extramolecular water
Lose on drying = Extramolecular water + Non-volatile substance
| Is This Answer Correct ? | 1 Yes | 0 No |
Answer / g,kiran
BY m.c We can findout only water content in a drug
while LOD result gives water content solvent present in
substance. Thus, LOD content is always hIgher than M.C.
| Is This Answer Correct ? | 1 Yes | 0 No |
Answer / srinath
Moisture content how must water in present in the sample &
Lod how much water in that sample &non volatil solvents present that sample
| Is This Answer Correct ? | 1 Yes | 0 No |
Answer / ravi
what are the differences between empower-2 and empower-3 softawre
| Is This Answer Correct ? | 0 Yes | 0 No |
Answer / abdullah al mamun
Loss on drying measures all weight loss after heating to a specific temperature for a specific time. This value will include moisture as well as any volatile components or solvents that may be present.
Moisture content is only a measure of the water is present in sample
| Is This Answer Correct ? | 0 Yes | 0 No |
Answer / suresh babu
MC is used for only for determination of water content.
LOD is used for identification of organic volatile solvents.
| Is This Answer Correct ? | 5 Yes | 6 No |
Answer / prabahaker reddy
LOD --- THE SOLVENT PERCENTAGE IN THE PRODUCT.
MC --- THE WATER CONTENT IN THE PRODUCT.
| Is This Answer Correct ? | 6 Yes | 10 No |
why equlirium conatant of water have 14 value
what is LC - MS ? What its wide use in cro/pharmaceutical Industry
How we develop a method by HPLC for unknown compound,if we got three peaks with same response then how we can find out which one is our desired compound's peak without taking help of LC MS.
what is the difference between Tailing Factor & Asymmetry
8 Answers Ashish Life Science, BEC Chemicals, Jubilant,
why salisylic acid not using now days for disdolution calibration?
How do we fix the sample concentaryion in hplc method development?
what is dissolution
please explain about aluminium hydroxide assay
what is the procedure for cleaning of lenses of hatr accesory of ftir instrument?
How to determine the EDTA content by potentiometry titration in Ceftriaxine sodium
What is the principle of GC/HPLC ?
4 Answers BioCan, Biocon, Megafine Pharma,
what is the difference between IR and FTIR instrument analysis
Organic Chemistry 
