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Analytical Chemistry Interview Questions
Questions Answers Views Company eMail

What are the different types of columns used in HPLC

Wockhardt,

3 13152

In HPLC when we use Isocratic method, Gradient method in hplc?

Pharmaceutical,

8 22477

Any molecule is filing for ANDA purpose, what are the dissolution requirements / specifications needed ?

IPCA,

1 6356

What is Endcapped Hplc column

 2 9666

Why we more noise in PDA detector compared to UV detector?

Aurobindo,

1 11641

if the purity is 99.9%,is need to do assay?

Reddy Labs,

3 15161

What is the difference between specified impurity and Identified impurity

Glenmark,

3 16201

What is the difference between specified impurity and Identified impurity

Merchant Navy,

1 6070

how do you established the RRF for unknown impurity

Square Pharma,

6 13126

I want analyze my compound at 325 nm so which standard shall i use to calibrate my HPLC system? How i can assure my hplc detector is suitable or not?

AMRI,

3 10120

How we will choose pH of a mobile phase if analyte pKa value is 4

Celon Labs, Laurus,

2 11384

what parameters we will consider while developing a HPLC method and how we confirm our HPLC method is valid?

DRL, Laurus,

3691

Which column is more polar, C8 or C18?

Cipla, Glenmark, Laurus, Torrent Power,

6 30383

what is the difference between heavy metals and sulphated ash

Aurobindo,

2 18113

what is difirence b/w ROI&ROE

Pfizer,

1 9665

Post New Analytical Chemistry Questions

Un-Answered Questions { Analytical Chemistry }

Why we check moisture,ash & AIA in product

1881

What is rs test why we are performing rs test?

1859

If inhouse hplc related substance method is completly diffrent from Usp for finished proďuct with diffrent impurities then how require to prove method equivalecy?

772

How can the GC or HPLC method is selected to determine the impurity profile in drug product?

7596

what is the acceptance criteria for enteric coated tablets in 0.1n hcl validation in each parameter?

889

what is mean by nitrosamine impurities?

1066

why lactose has less charges when packed in steel containers when compared with packing of lactose in polyamide material?

2298

for which product require to do content uniformity? what is limit of cu?

817

For standardization of volumetric solutions, acceptance limit for concentration is considered as 10% of nominal concentration and %RSD as NMT 0.2% (for appropriate no. of replicates). But , if %RSD has not met, what should be further action?

1907

What is the purpose of octyl silane columns?

4290

what is difference in ods I ods II is this is realy from sorbent / packing characteristics or from other means

1972

What is shaking level in GC?

792

What is the Formula for coreletion coefficient in plhplc calibration

1830

how to get accurate result for Residue on evaporation in purified water

1647

why octanol used to determine the partition coefficient ?

2458

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