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Analytical Chemistry Interview Questions
Questions Answers Views Company eMail

What are the different types of columns used in HPLC

Wockhardt,

3 11560

In HPLC when we use Isocratic method, Gradient method in hplc?

Pharmaceutical,

8 19872

Any molecule is filing for ANDA purpose, what are the dissolution requirements / specifications needed ?

IPCA,

1 5397

What is Endcapped Hplc column

 2 8681

Why we more noise in PDA detector compared to UV detector?

Aurobindo,

1 10666

if the purity is 99.9%,is need to do assay?

Reddy Labs,

3 13896

What is the difference between specified impurity and Identified impurity

Glenmark,

3 14769

What is the difference between specified impurity and Identified impurity

Merchant Navy,

1 5088

how do you established the RRF for unknown impurity

Square Pharma,

6 11338

I want analyze my compound at 325 nm so which standard shall i use to calibrate my HPLC system? How i can assure my hplc detector is suitable or not?

AMRI,

3 8737

How we will choose pH of a mobile phase if analyte pKa value is 4

Celon Labs, Laurus,

2 10311

what parameters we will consider while developing a HPLC method and how we confirm our HPLC method is valid?

DRL, Laurus,

3105

Which column is more polar, C8 or C18?

Cipla, Glenmark, Laurus, Torrent Power,

6 27844

what is the difference between heavy metals and sulphated ash

Aurobindo,

2 16724

what is difirence b/w ROI&ROE

Pfizer,

1 8500

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Un-Answered Questions { Analytical Chemistry }

Home heating oil or furnace oil what is made from? Can (base oil plus diesel/kerosen) = home heating oil?

1692

Difference between hlaf and rlaf

1650

what is different when impergnated silica plates are used in separation of azo dyes using column chromatography?

1518

What is the purpose of octyl silane columns?

3787

is it necessary to do HPLC calibration at wavelength 315nm if we are doing analysis at this wavelangth

1661




Identify problem faced when mass spectroscopy is used with HPLC system ?

1375

in which situation require to use paddle and basket?

287

How to calculate coreletion coefficient

1138

what is turbidimetric titration?Give 2 examples.

1986

What is the difference between spectro meter and spectro photo meter?

10415

How can I develope method of dissolution by HPLC OR UV

1893

how you fix the limits of impurities?

376

can we use the same detector in HPLC as well GC and what could be the differences we can find in the final chromato graph in any aspects?

1702

what you do when compound having dwel wavelength?

280

Principle of single pan analytical balance

4598

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