If change in specification which parameter require to do for validation? if change in chromtographic condition then which parameter? if api change then which parameter? if change composition then which parameter? if old method not work out then whicj parameter? if additional one impurity added then which parameter of validation require to do on above each conditions? elaborate separately

0 Answers  

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gc Calibration % RSD failed what is the possible reasons?

5 Answers   Divis Laboratories,

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What is the difference between chiral cel OD-H & OD-RH ?

3 Answers   Aptuit Laurus,

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WHY POTASSIUM HYDROGEN PTHALATE IS USED FOR PERCHLORIC ACID? What is difference btw UV detector & RID detector? what is dissolution? What is unit of KF? what is the significant of pH in HPlc?

1 Answers  

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What is Spliit and Splitless in Gas Chromatography nad How does it work?

4 Answers   Sterling,

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what is regration method in method validation , how we can calculate it.

3 Answers   Cipla, Sun Pharma,

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what is least count of a balance? How we find out this? Any formula for least count of Analytical balance?

13 Answers   Acme Formulation, Analytical Solutions, Dr Reddys, Reddy Labs,

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why using buffers in hplc inteed of water

5 Answers  

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today i am doing calibration of HPLC. when i inject the blank it was going on -ve.(bleow then zero) why?

3 Answers  

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What impact analysis required for out of calibration and how to proceed

2 Answers   Aventis,

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If combination product how require to identify which imp is of which api?

0 Answers  

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Why irmoisture balance is used for corrugated box moisture testing

0 Answers   Leiutis, Lupin,

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