Answer / murali reddy

We have to 're check why it has failed.For example wavelength accuracy failed means we have to do impact analysis
That is before calibration of HPLC ..Which products are analysed
The same products (same test) had to repeat on another system
Like this last 5 samples need to analysed.if results are ok
We can say no impact.Then after knowing actual problem
Re calibration required n proper justification should be given.

Answer / pranav

IN CASE OF OUT OF CALIBRATION AN EXTERNAL AGENCY WILL
CALIBRATE THE INSTRUMENT

Describe your experience with quality assurance and quality control analyses?

11 Answers   Aurobindo, Dr Reddys, MSC, Reddy Labs,

---

why we use holmiumperchlorate in calibrating uv

4 Answers   Aurobindo, DRL, MSN Pharma,

---

what is MCG dilution in HPLC & GC analysis

1 Answers   Amoli Organics, Cipla,

---

why buffer is added in solvent system in HPLC ??

10 Answers   Lupin,

---

why KF factor is between 4.5 to 7.5 mg/ml ? why ? why sometime pyridine is used in analysis like in raw material solvent like acetone etc?

11 Answers   Aurobindo, GVK, Sohan Healthcare,

---

In the test for control of absorbance in UV calibration why do we use only potassium dichromate and what is purpose of taking a specified amount of 57.0-63.0mg?

8 Answers   Aurobindo, Cipla, FDC,

---

how peak can be sharp in hplc when it is come flat

6 Answers   Graviti Pharmaceuticals,

---

how much you expected salary?

7 Answers   GSK GlaxoSmithKline,

---

how many types of Proceing methods?

8 Answers   Reddy Labs,

---

why the ph scale range is 1 t0 14 and why not beyond 14 and not to below 1?

5 Answers   Avra, Granules, Orchid,

---

What should be the calibration procedure for wavelength accuracy in case of HPLC?

4 Answers  

---

What is the role of SO2,I2, Methanolic hydroxide and any base in Karlficher titration

2 Answers   Medley Pharmaceuticals,

---