Interested to Buy Any Domain ? << Click Here >> for more details...
How to develop the method when we have very low amount of
impurity?
- 2 Answers
- 8416 Views
- I also Faced
- E-Mail Answers
Answers were Sorted based on User's Feedback
Answer / kalpana
by doing the force degradation of the sample in different
condition(like acid, alkali, peroxide,thermal and
photolytic degradation)and then develope the method.
| Is This Answer Correct ? | 14 Yes | 2 No |
Answer / balaji
IN THIS CASE INCRESE SAMPLE CONCENTRATION EG; MY DRUG KNOW
IMPURITES LIMIT IS 0.05% UNKNOW IMP LIMIT IS 0.03% INTHIS
CASE STD PREPARATION IS 5MG/100 FURATHER 1/100 THIS IS KNOW
IMPURITES CONCENTRATION 3/100 AND 1/100 THIS UNKNOW IMP
MEANS API, SAMPLE CONCENTRATION IS 1MG/ML IF STD AREA IS
NOT COME INCRESE THE SAMLE CONCENTRTION MEANS
10/100*1/100*10/20*100=0.05% SAMLE CONCENTRATION IS 2MG/ML
| Is This Answer Correct ? | 1 Yes | 3 No |
How to calculate the maximum loaded sample concentration in HPLC column?
What is delay volume?
When you get Moisture content by KF higher than by LOD, what does this indicate?
What is unit of KF?
why we inject sample TWICE in ASSAY by HPLC analysis but in RS once?
4 Answers Aurobindo, DRL, Neuland,
Can anybody tell me how to measure Redox potential in an aerobic matrix, for e.g., soil etc.?
Why we used in n-butyl acetate water content terminology while in ethyl acetate we used moisture content terminology?
In standard weight box used for calibration of analytical balance there are two numbers (Qty) of 20mg, 200mg,2.oGM weights. Why?
Why KBR is used in IR for preparation of pellete, why it shows zero dipole moment
In pharmaceuticals formulation OOS applicable in Raw Material(which is not manufacturing in the company. and purchase by approved vendor)).Why?
difference between precision & accuracy.
why holium oxide prepared in 10% HCLO4 SOLUTION
Organic Chemistry 
