why results are variation in same samples analysis in gc
and hplc ?

Answers were Sorted based on User's Feedback



why results are variation in same samples analysis in gc and hplc ?..

Answer / vishal shah

In GC analysis due sample preparation error, if your sample
is open in air so your result may down from initial
analysis,another is during sample preparation if your
tablet crush in morning and you take weight in afternoon
may result is down, Preparation-1: during sample
preparation first you weight crushed tablent in head space
vial than add diluent after all weight(if Time gape between
wieght and adding diluent).
Preparion :-2 During sample preparation first you add
diluent and than add sample may you resule higher than
prepartion :-1

Is This Answer Correct ?    11 Yes 1 No

why results are variation in same samples analysis in gc and hplc ?..

Answer / suhas

Different detector givs different reponse for same sample,
i.e. HPLC have UV or RI and GC have FID or TCD.

Is This Answer Correct ?    5 Yes 3 No

Post New Answer

More Analytical Chemistry Interview Questions

What is the diffrence in japan mkt requirement in analytical method validation over US?

0 Answers  


why urasil use in hplc column perfomance?

1 Answers   Bayer,


What is the difference between Discriminating media and DPDM(Dissolution Profile with Different Media)

0 Answers   Natco,


Why do we use sodium salicylate for Calibration TLC Cabinet U.V Lamps

3 Answers   Matrix, Spar Labs,


What is the importance of sulphated ash test?

1 Answers  






if instrument calibration fails then what require to do?

0 Answers  


What is the Calcultion of S/N Ratio.

2 Answers  


How to make up 100ml of a solution cintaining compound A at 95µg/ml and compound B at30µg/ml for an HPLC reference standard.

3 Answers  


What is the formula to determine the concentration of M of a solution given the % transmittance? Use %T = 43.7 as an example.

0 Answers  


Why we use Caffeine in hplc calibration

2 Answers   Emcure, Laurus,


Weight balance variation limit during analysis

7 Answers   Amneal Pharmaceuticals,


Which parameters require to do in tech transfer?

0 Answers  


Categories
  • Organic Chemistry Interview Questions Organic Chemistry (342)
  • Inorganic Chemistry Interview Questions Inorganic Chemistry (123)
  • Analytical Chemistry Interview Questions Analytical Chemistry (1387)
  • Physical Chemistry Interview Questions Physical Chemistry (62)
  • General Chemistry Interview Questions General Chemistry (478)
  • Chemistry AllOther Interview Questions Chemistry AllOther (190)