why we are analyzing purity on HPLC why not in gc
- 3 Answers
- 13277 Views
- Aurobindo, Reddy Labs, I also Faced
- E-Mail Answers
Answers were Sorted based on User's Feedback
Answer / sunil tiwari
Purity can be perform on the both the instrument HPLC as well as on GC, difference is that the:
1) If material is volatile in nature or can be converted easily in to the gaseous form, purity can be perform on GC, also material should be free from other substantial matters
2)If material is non-volatile, less volatile in nature or in liquid form, purity can be perform on HPLC,
| Is This Answer Correct ? | 34 Yes | 1 No |
Answer / sandip bhasme
GC has it's own limitations. You cannot analyse non volatile
/ very high boiling point materials on GC. Commonly, If you
are using FID GC, You won't get polymer / inorganic
impurities on your chromatogram.
| Is This Answer Correct ? | 32 Yes | 1 No |
Answer / kala
HPLC is a nondestructive method,gc is destructive
| Is This Answer Correct ? | 4 Yes | 18 No |
What is the difference between chromatographic purity and related substances?
Is there any difference in principal of reverse phase and normal phase chromatography? and why? Please update. Thank and regard
which light is used in FT-IR spectroscopy
how calibrate the hplc detector
2 Answers Cipla, Shraddha Analytical Services,
What is heavy water
Retention time & Relative Retention time Definition & between difference? How to Calculate response factor(RF) & relative response factor(RRF)?
What is the diffrence in japan mkt requirement in analytical method validation over US?
In case of HPLC coloums what is the difference Between C8 & C18 coloums & how can we select difference type of coloums like Inertial ODS , Hypersil BDS , ODS etc.?
How we can perform Linearity study for validation by HPLC with very low conc of sample
how to regulate noise in HPLC?
2 Answers Alkem Labs, Vimta Labs,
How to estimate potassium?
WHICH STANDARD WE USE IN SILICA ANALYSIS IN SILICA-GEL METHOD FOR SOLID SAMPLE
Organic Chemistry 
