If change in specification which parameter require to do for validation? if change in chromtographic condition then which parameter? if api change then which parameter? if change composition then which parameter? if old method not work out then whicj parameter? if additional one impurity added then which parameter of validation require to do on above each conditions? elaborate separately

0 Answers  

---

Is it necessary to inject three replicate for accuracy in AMV.

1 Answers   Amoli Organics,

---

As per USP u/vacuum means (how much vacuum should be applied)?

1 Answers   Mylan,

---

WHAT IS THE USAGE OF REFRACTIVE INDEX IN PHARME FIELD

3 Answers  

---

why IR graph or spectra comes down ? Any reason

4 Answers  

---

how to calculate elemental impurities?

0 Answers  

---

difference between selectivity and specificity

2 Answers   Troikaa Pharmaceuticals,

---

what is RI detector Cut-off Value

1 Answers   Mylan,

---

if the purity is 99.9%,is need to do assay?

3 Answers   Reddy Labs,

---

What is the purpose of octyl silane columns?

0 Answers  

---

How we develop a method by HPLC for unknown compound,if we got three peaks with same response then how we can find out which one is our desired compound's peak without taking help of LC MS.

4 Answers   Apotex, Kemwell,

---

how much mass should be there in volumetric flask while in preparation of sample for assay? 

0 Answers   Reddy Labs,

---