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1.What is the difference between method validation and method verification
2.Which guidelines proposed to method transfer
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From where 16 or 5.545 is derived in theoretical plates calculation formula by USP or JP/BP/DAB and what is meaning of this coefficient and impact in calculation ?
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In BP2013, Loperamid HCl monograph. Assay by titration with 0.1N sodium hydroxide using hydrocloric acid 0.01N and reading the volume added between the 2 points of inflexion. I have a question that if the diluent solvent is ethanol is certainly consumed a amount of volume of titrant, so this volume must be eliminated on the result calculation or not apart from first point which is subtracted above.
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How can we determine Moisture content of HI?
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2 Answers Hikma Pharmaceuticals, Neuland, Reddy Labs,
Organic Chemistry 
