Interested to Buy Any Domain ? << Click Here >> for more details...
Difference Between End Cap HPLC Column and Non End Cap Column
- 2 Answers
- 14660 Views
- I also Faced
- E-Mail Answers
Answers were Sorted based on User's Feedback
Answer / samar mandal
In end capped column the no of free silanol groups are very less compared to non end capped column.A capping reagent like Cl(CH3)2SiCH3 is used to bond with the sillica bed apart from C8 and C18 group, which eventually block the free silanol group by forming silyl ether(-Si-O-Si-), which decreases the reaction between analyte and free silanol groups.
| Is This Answer Correct ? | 37 Yes | 1 No |
Answer / sagar flamingo ltd
In Case of End Cap Column both end are connected with SS Cap Which is easily removable.But In Case of without End Cap Column there are not having such type adjustment.
| Is This Answer Correct ? | 2 Yes | 11 No |
IS THERE ANY EQUIPMENT TO CHECK AND CALCULATE THE POLARITY OF A LIQUID?
what is impurity profile. how to interpret this impurity profile to a drug product or drug substance.
what is different between volumetric solution and general solution
some compound havving uv region but not give much more response during hplc analysis
why does used dry caffien in HPLC calibration?
What is related substance by HPLC impurity limits as per USP?
what is DIPE limit in residual solvent?
what is the different in Total ash, sulphated ash, acid insoluble ash, alcoholic or non alcoholic ash?
What is post run in hplc?
In IR spectra, generally a molecule vibrates without apply emr or ir light?
what is the acceptance criteria for enteric coated tablets in 0.1n hcl validation in each parameter?
How to caluculate the RRF and correction factor in hplc
1 Answers Alkem Labs, Aurobindo, Rakshit Drugs, SDLPL,
Organic Chemistry 
