In Force degradation Study Compound is not degrade in any condition , also in

In Force degradation Study Compound is not degrade in any
condition , also in higher stress what can i do ?

Question Posted / dinesh111981

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In Force degradation Study Compound is not degrade in any condition , also in higher stress what c..

Answer / venkatramireddy

you did all conditions means
acidic,basic,hydralytic,peroxide,photolytic conditons,but u
did not get any degration analyte,u have to do one thing u
have to increase concentrations or time,still not
degrade,then u have to give justification,Declare drug to
be practically stable.

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In Force degradation Study Compound is not degrade in any condition , also in higher stress what c..

Answer / developer

then ur drug is rock stable. we have to check the
degradation in acidic basic peroxide heat humidity and light
exposures. degradation depands on the functional groups
present in the molecules.

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In Force degradation Study Compound is not degrade in any condition , also in higher stress what c..

Answer / anudeep babu

increase the refluxing(HEAT) time or temperature and maintain the all the conditions with in the ICH limit...........or else increase the refluxing(HEAT) time........

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0 Yes

2 No

In Force degradation Study Compound is not degrade in any condition , also in higher stress what c..

Answer / anudeep babu

increase the refluxing(HEAT)time or increase the refluxing temperature and maintain all the parameters within the ICH limits.......

Is This Answer Correct ?

1 Yes

4 No

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