Interested to Buy Any Domain ? << Click Here >> for more details...
Is sonication essential in solubility testing of a drug
substance?
- 6 Answers
- 16401 Views
- Aurobindo, I also Faced
- E-Mail Answers
Answers were Sorted based on User's Feedback
Answer / hemant mhaske
FOR THE SOLUBILITY TESTING SONICATION IS NOT REQUIRRED B,COZ WE ARE DETERMINING SOLUBILITY OF COMPOUND IN SUITABLE SOLVENT. MEANS IN WHICH SOLVENT IT IS FREELY SOLUBLE AND IN WHICH SOLVENT LESS SOLUBLE..
| Is This Answer Correct ? | 11 Yes | 0 No |
Answer / pharmainterview
There is no guideline which specifies the sonication
required or not for solubility. So some people prefer to
sonicate and other not. You can't say which one is wright
because you have no evidenced guideline.
Regards
pharmainterviewquestions.blogspot.in
| Is This Answer Correct ? | 8 Yes | 2 No |
Answer / manjeera
sonication is not exactly required for a solubility test of drug substance it is preferable sometimes to check whether it is soluble when it is sonicated.
| Is This Answer Correct ? | 5 Yes | 1 No |
Answer / pradeep reddy
no need to use of sonicate.because substances will freely
soluble in diluent.by hand shake or spinic we can do that
test.
| Is This Answer Correct ? | 2 Yes | 1 No |
Answer / msreddyvelagala
sonication is not mentioned in usp&EP.solubility is checked by handshaking for 1 minute &put it at temperature 20 or 25c for some time.
| Is This Answer Correct ? | 1 Yes | 0 No |
Answer / devendra
There is no need to sonication if it say very soluble, freely soluble, soluble...
In case of practically soluble we can use sonication.
| Is This Answer Correct ? | 2 Yes | 1 No |
WHAT IS DIFFERENCE B/W MALTINGRANG/DSC
which chromatographic technique is used for softening hard water?
what is the method of UV cabinet CALIBRTION
Why we have to use KBr pellet technology ?
my name is santhosh i cmpleted b.pharmacy in 2009 then i went to uk in 2010 to pg diploma business management. after i came back to india.. recently again apply to uk for pharmaceutical analysis. they refused my visa you failed to explain y u r change subject. so plz ineed answer for y change the cource
why using the ph 4,7,9.2?
why sucrose used in polarimeter calibration?
2 Answers Reddy Labs, Sugar Factory,
In HPLC (Waters) software Empower1,2 &3 what is the updation for each version
For LOD and LOQ determination which method is accurate? (slopemethod or s/n ratio method)
What is control room temperature and which guide line says?
What are the primary considerations in extractables and Leachables ?
how to prepare 5normality of hcl
Organic Chemistry 
