What is the difference between HPLC and GC?

Answers were Sorted based on User's Feedback



What is the difference between HPLC and GC?..

Answer / kanakadurga

In Hplc the principle is adsorption it is applicable for
separation of non volatile solutions.
where as in Gc the principle is partition it is applicable
for separation of volatile compounds.

Is This Answer Correct ?    43 Yes 4 No

What is the difference between HPLC and GC?..

Answer / aprao22@gmail.com

HPLC:mobile phase is liquid and stationary phase solid(silanes)
L=max 250 mm
Separarion:Based on adsorption
GC: mobile phase is gas and stationary phase liquid coated solid(silaxoneas)
L=30M
Separarion:Based on partition

Is This Answer Correct ?    1 Yes 0 No

What is the difference between HPLC and GC?..

Answer / manisha

In hplc sample is partitioned between 2 phases and it is applicable for non volatile compounds whereas in cg adsorption phenomenon is taking place and mainly useful for volatile compounds.

Is This Answer Correct ?    10 Yes 11 No

Post New Answer

More Analytical Chemistry Interview Questions

Why monograph of hplc coming upperside of drift but in IR monograph coming in drift side?

1 Answers  


How to calibration of the uv spectroscopy and its test?

0 Answers  


What is differences between the Instrument and Equipment

2 Answers   Aurobindo,


What is the difference between known and unknown impurities?

1 Answers  


Which parameters require to do in tech transfer?

0 Answers  






all types of questions asked at the cipla interview

0 Answers   Aurobindo, Calyx, Cipla, Graviti Pharmaceuticals,


From where require to take the RLD sample?

0 Answers  


why linerity not use in GC but use in HPLC ?

6 Answers  


In capadity factor formula is K'= (RT of main compound/RT of first eluted peak)-1 in this formula what is 1

1 Answers   Piramal Healthcare,


How long we can use hygroscopic reference standard in terms of water absorb.I mean in line with respective monograph's specification or more than that?

1 Answers  


what is use of acetonitrile compare to methanol in RP-HPLC Method devlopment

7 Answers   Neuland, Orchid,


why are not used methonol in kf titrator to find out water content in ketones?

5 Answers   Piramal Healthcare,


Categories
  • Organic Chemistry Interview Questions Organic Chemistry (342)
  • Inorganic Chemistry Interview Questions Inorganic Chemistry (123)
  • Analytical Chemistry Interview Questions Analytical Chemistry (1387)
  • Physical Chemistry Interview Questions Physical Chemistry (62)
  • General Chemistry Interview Questions General Chemistry (478)
  • Chemistry AllOther Interview Questions Chemistry AllOther (190)