Wt s the use of linearity in HPLC method validation
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Answer / priyesh mistry
To establish the working range of your product/impurity of
interest with respect to the specification mentioned. Also
it is demonstreting that by doing plot for repsonse V/s
concentration linear relation must be seen. It also
justifies that my response is directly proportional to the
concentration of the analyte present.
| Is This Answer Correct ? | 40 Yes | 0 No |
we are proving the concentration of sample is directly
proportion to area response, why we have to do this means
during stability studies some time we will get above and
below the specification, here linearity is proving your
method is giving linear
| Is This Answer Correct ? | 3 Yes | 0 No |
Answer / parag parekh
TO CONFIRM THE RESPONCE of detector & instrument with the
concentration wheter the system is responding properly for
the change in concentration.
| Is This Answer Correct ? | 2 Yes | 2 No |
Answer / basha
to plot conc.vs area responce to give regression staight
line or coefficient of correlation 0.98
| Is This Answer Correct ? | 5 Yes | 10 No |
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Organic Chemistry 
