Interested to Buy Any Domain ? << Click Here >> for more details...
Wt s the use of linearity in HPLC method validation
- 4 Answers
- 16691 Views
- I also Faced
- E-Mail Answers
Answers were Sorted based on User's Feedback
Answer / priyesh mistry
To establish the working range of your product/impurity of
interest with respect to the specification mentioned. Also
it is demonstreting that by doing plot for repsonse V/s
concentration linear relation must be seen. It also
justifies that my response is directly proportional to the
concentration of the analyte present.
| Is This Answer Correct ? | 40 Yes | 0 No |
we are proving the concentration of sample is directly
proportion to area response, why we have to do this means
during stability studies some time we will get above and
below the specification, here linearity is proving your
method is giving linear
| Is This Answer Correct ? | 3 Yes | 0 No |
Answer / parag parekh
TO CONFIRM THE RESPONCE of detector & instrument with the
concentration wheter the system is responding properly for
the change in concentration.
| Is This Answer Correct ? | 2 Yes | 2 No |
Answer / basha
to plot conc.vs area responce to give regression staight
line or coefficient of correlation 0.98
| Is This Answer Correct ? | 5 Yes | 10 No |
Polarized meter calibration, 1. Method name? 2. Which solution use? 3.why?
What is peak purity and response factor in chromatographic analysis? Why we required to find out response factor?
why we are doing seal wash and needle wash?
why 2Theta value is consider in the XRPD spectra and how to consider the 2 Theta value
importance of internal standard and in what conditions it is used?
What is the difference between Paddle and Basket Why we are using Basket or paddle in dissolution.
7 Answers Apotex, Cipla, GSK, Intas, Zydus Cadila,
What is unit of KF?
why we are using sodium,potassium phosphates for mobile phase preparation?
What attracted you to analytical chemistry?
function of detecter in hplc ,gc and spectroscopy? function of carrier gas in gc?
If we have 5 strength which is not dose proportinate and excipients also diffrent in each strength then how we can proceed for Force degradation? and excipient are same but not dose propotinate the how FD?
1.What is the difference between method validation and method verification 2.Which guidelines proposed to method transfer
Organic Chemistry 
