What is the difference between Paddle and Basket Why we are
using Basket or paddle in dissolution.
Answers were Sorted based on User's Feedback
Answer / maulik
paddle and baskets are the different type of the apparatus
used in dissolution to find the drug release.
generally, baskets are used for capsule or ur tablet
flotting in media. paddle can be used for all. some times
paddle is also used in the capsule and flotting tablets by
using sinker to achieve appropriate result
| Is This Answer Correct ? | 74 Yes | 21 No |
Answer / dhiraj kumar
Generally we are using basket in those tablets in which HPMC is using as a binder because if HPME will come to contract with water then it will show sticky correcter and the tablet in which HPMC is used as a binder will get swell and stick with vessel and drug is not release because tablet will not move properly but in basket tablet is in the center of the vessel and so drug will release continue.
| Is This Answer Correct ? | 52 Yes | 6 No |
Answer / afan ahmad
paddle and Basket both are uesed for tablets and capsules
Generally we are using basket in those tablets or Capsules in which HPMC is using as a binder or sticky binder or sticky material used either stick lower side of vessel or side of vessel at top point
Result-Released of every Tablet or capsule in every vessel is totally different at different point or time ot interval
Paddle may use for Tablets or Capsules either floating with the help suitable sinker
| Is This Answer Correct ? | 8 Yes | 4 No |
Answer / devender
basket used to avoid hpmc contact to the vessels
| Is This Answer Correct ? | 0 Yes | 0 No |
Answer / rameshkunchala
Mainly difference between paddle used for more active drug and basket used in mainly low contain and capsule sr sustained release
| Is This Answer Correct ? | 4 Yes | 5 No |
baskets are used for low average weight tablets&low active integrated tablets and also genitic coated tables
| Is This Answer Correct ? | 5 Yes | 8 No |
Answer / sadhu babu
Baskets are used for low average weight & low active ingredient tablet, high average weight tablets,low average weight tablets with sinkers are paddle used
| Is This Answer Correct ? | 0 Yes | 3 No |
How to do spike of aflatoxin in peanut to get maximum recovery
what is biorelivent dissolution media?
why the most API molecule are in the hydrochloride form?
What is Delay & Dead Volume
perchloric acid&glacal acetic acid both are acids but reaction is complete in volumetric titrations.how?
WHAT IS THE DIFFERENT BETWEEN PURITY, POTENCY AND ASSAY
In UV calibration we use Holmium perchlorate solution made in 1.4M perchloric acid The question is that 1.4 M perchloric acid we make is it in water or glacial acetic acid?
how will you do the prep for unstable componds?
0 Answers AMRI, CTX Life Sciences, Piramal Healthcare,
Describe your experience with analytical instrumentation?
3 Answers Alembic, Apotex, Aurobindo, DLF, Enal Drugs, Lupin, Natco, Pharma,
How require to develop GC method? how to select diluent, GAS, column selection and other chromatographic conditions?
how you establish the LOQ?
why KF factor is between 4.5 to 7.5 mg/ml ? why ? why sometime pyridine is used in analysis like in raw material solvent like acetone etc?
11 Answers Aurobindo, GVK, Sohan Healthcare,