From where 16 or 5.545 is derived in theoretical plates calculation formula by USP or JP/BP/DAB and what is meaning of this coefficient and impact in calculation ?
2 12864can we use the same detector in HPLC as well GC and what could be the differences we can find in the final chromato graph in any aspects?
2180Home heating oil or furnace oil what is made from? Can (base oil plus diesel/kerosen) = home heating oil?
2184What is the principle of HPLC, GC, LCMS, GCMS,LC QQQ, GC QQQ, LC Q TOF and GC Q TOF. What are the applications and Specificity?
8862What is the difference between Spectroscopy and spectrophotometry,What are the applications?
4 11887Post New Analytical Chemistry Questions
why we use a particular hplc column for a particular compound give reasons?please
Did anybody have method for acetyl cysteine effervescnce tablet
in dissolution if one bowl got 70 percent 2nd bowl got 80 percent and 3rd bowl got 90 percent then how proceed?
In HPLC (Waters) software Empower1,2 &3 what is the updation for each version
if content uniformity passing but dissolution varrying then what is next step?
AT WHAT CONDITIONS WILL YOU ANALYSE A SAMPLE,WHICH ARE PRESERVED AT OTHER THAN THE AMBIENT CONDITIONS?(ie COLD STORAGE SAMPLES BELOW 20* CENTIGRADE?
How do we get end points and how many end points are possible for citric acid and di-acid not theorotically answer should be given practically.
Why dissolution test is not performed in all of the products
please explain about aluminium hydroxide assay
give clarity of linearity and range in method validation
how to develop the icp ms method? Application of icp ms?
inhouse product is in capsule form in combination and RLD is in tablet form then can we proceed for multimedia CDP? in inhouse capsule product disso is paddle with sinker in release media is there then RLD product in tablet form then with same as paddle with sinker we can proceed n.a.?
how you confirm the assay method?
some product having water content method with pyridine and ethylene glycol mixture instead of methanol? how they are selecting and methanol is not suitable solvent how ?
In HPLC calibration, caffeine is used as primary standard for wave length calibration due to caffeine is having dual maxima at 273 & 205 nm and one minima at 245 nm. Any body can give reference of these details from any pharmacopeia (with chapter no.) or any other authentic guideline?