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In my analysis by HPLC,In sample main peak and placebo peak are eluting with shorter resolution ( almost look like doublet). how can i get max resolution ? Is changing gradient method is usefull?
3 12587why SGF media used for dissolution . What is the use of it .can we use other media of lower pH instead ot this?
1 8691How do we get end points and how many end points are possible for citric acid and di-acid not theorotically answer should be given practically.
2584For Recent draft guidelines for Dissolution test apparatus calibration, why removing the salicylate tables?
3 10530Post New Analytical Chemistry Questions
we are performed SOR for a particular product the limit is -6 to -10.We face particular bathes it is not meeting the specification.we performed diffrent instrument diffrent analyst we are getting diffrent diffrent results.solvent is dimethyl sulfoxide what could be the reasion
how you start the solubility study?
How to fix the sample conc. in Related substances test by HPLC?
if content uniformity passing but dissolution varrying then what is next step?
Please tell me about the pH of Polycaboxylic ether is it in the 5-6 range ever or more than 6
Why acetonitrile and water are used as extraction solvent when analysis melamine? I thought they are miscible and won't be able to separate...
In which situation we require to analytical method validation of excipient?
Why only Copper standard is used to calibrate Atomic Absorption spectrophotometer?
What is control room temperature and which guide line says?
How to set analyticl specification for combination products?
Why sodium hydroxide used for maintain pH of phosphate buffer
What is shaking level in GC?
If suppose 10 methods of dissolution given in pharmacopoeial for single content product then which method out of 10? or all 10 require to follow?
Which parameter require to do for analytical method equivalency?
why multimedia dissolution require to do?
