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Analytical Chemistry Interview Questions
Questions Answers Views Company eMail

In my analysis by HPLC,In sample main peak and placebo peak are eluting with shorter resolution ( almost look like doublet). how can i get max resolution ? Is changing gradient method is usefull?

3 12742

what is the need of calulation of RRF of impurity in HPLC analysis?

9 32175

why SGF media used for dissolution . What is the use of it .can we use other media of lower pH instead ot this?

1 8755

what is difference between UV - VISIBLE MODEL NO like 1600,1601,1700 etc ? plz explain me

Graviti Pharmaceuticals,

2736

How do we get end points and how many end points are possible for citric acid and di-acid not theorotically answer should be given practically.

Hetero, Reddy Labs,

2631

only one end point is possible for citric acid and we get 2 end points for di acid why?

Reddy Labs,

3 8679

why kf factor coming 0.5

Alkem Labs,

5 17929

For Recent draft guidelines for Dissolution test apparatus calibration, why removing the salicylate tables?

Alkem Labs,

3 10656

How can v calibrate ftir ? Plz explain me

Cipla,

2 20064

what is the diff betwen calibration and system suitability?

8 22340

Why Methanol used in KF Titration?

Glenmark, Lupin,

15 68499

Why do we use 500ppb sucrose and 500ppb 1,4 benzoquinone in TOC calibration?

Vardhman,

2 9307

why chiral separation?

1 8637

what is main use of primary standards in caliration

Lee Pharma, Lupin, Nectar Lifesciences,

2 6497

what are the important specifications for a Column ?

2 10312


Post New Analytical Chemistry Questions

Un-Answered Questions { Analytical Chemistry }

How will u perform degradation study in detectors other thann PDA in HPLC Methodology

2600


What is delay volume?

1436


for which product require to do content uniformity? what is limit of cu?

878


What should be the level/ Percentage of Arsenic in Arsenic free zinc.

2276


what is lod and loq ?,why use k2cr2o7 , kcl h2so4 in uv calibration ?,why use benzophenone & caffene acetone in hplc calibration ?,what is leading peak in hplc ?why we do the calibration of limit of stry light in hplc & uv ?

3727


what is impurity profile. how to interpret this impurity profile to a drug product or drug substance.

2682


how you fix the limits of impurities?

894


What is stray light in uv what are units for stray light

1721


why octanol used to determine the partition coefficient ?

2499


Which parameter require to do for analytical method equivalency?

820


what is different when impergnated silica plates are used in separation of azo dyes using column chromatography?

2079


How we performed the force degradation for drug substance, is any specific guideline is available for each parameter(Acidic, basic, oxidation,heat)? what conditions you mentained for above parameters.

2360


i want model written test paper for the post of analyst in IOCL(indian oil corporation ltd) any one pls help me

2783


how to develop the icp ms method? Application of icp ms?

850


What is split ratio in Gc? Splitless? how requirr to select?

943