Analytical Chemistry Interview Questions
Questions Answers Views Company eMail

In my analysis by HPLC,In sample main peak and placebo peak are eluting with shorter resolution ( almost look like doublet). how can i get max resolution ? Is changing gradient method is usefull?

3 11259

what is the need of calulation of RRF of impurity in HPLC analysis?

9 28460

why SGF media used for dissolution . What is the use of it .can we use other media of lower pH instead ot this?

1 7853

what is difference between UV - VISIBLE MODEL NO like 1600,1601,1700 etc ? plz explain me

Graviti Pharmaceuticals,

2232

How do we get end points and how many end points are possible for citric acid and di-acid not theorotically answer should be given practically.

Hetero, Reddy Labs,

2057

only one end point is possible for citric acid and we get 2 end points for di acid why?

Reddy Labs,

3 7325

why kf factor coming 0.5

Alkem Labs,

5 15606

For Recent draft guidelines for Dissolution test apparatus calibration, why removing the salicylate tables?

Alkem Labs,

3 9166

How can v calibrate ftir ? Plz explain me

Cipla,

2 17757

what is the diff betwen calibration and system suitability?

8 19573

Why Methanol used in KF Titration?

Glenmark, Lupin,

15 63685

Why do we use 500ppb sucrose and 500ppb 1,4 benzoquinone in TOC calibration?

Vardhman,

2 8107

why chiral separation?

1 7790

what is main use of primary standards in caliration

Lee Pharma, Lupin, Nectar Lifesciences,

2 5311

what are the important specifications for a Column ?

2 9027


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Un-Answered Questions { Analytical Chemistry }

why require to do water content for drug product?

320


Why a1% value is used for some product ? What is the criteria for selection a1% value ?

1876


[3/30, 13:29] Manoj P Venkatpurwar: How hplc column selection according to structure? How mobile phase buffer selection on molecule structure?

317


How we can identify process related and degradation impurity in single method with short period?

340


How can we calculate "confidence interval" in analytical method validation? Pl. explain with example.

3603






before starting analytical method valodation what you checking? and how giving preference to start validation?

353


how to select short coloum and long coloumn for new molecule

1824


How can we calculate offset value pH measurment

1075


all types of questions asked at the cipla interview

4139


if your product is soluble in 0.1n hcl and water then which you choose as media from these 2 media?

280


What is the Formula for coreletion coefficient in plhplc calibration

1255


we are performed SOR for a particular product the limit is -6 to -10.We face particular bathes it is not meeting the specification.we performed diffrent instrument diffrent analyst we are getting diffrent diffrent results.solvent is dimethyl sulfoxide what could be the reasion

1362


could negative ions be produced by bombardment process in mass spectrometry?

1299


how pda detector works over uv?

297


acceptance criteria for lod & loq by standard deviation of response and slope??

2099