Interested to Buy Any Domain ? << Click Here >> for more details...
How to calculate mass balance in RS after degradation
- 1 Answers
- 6108 Views
- Reddy Labs, I also Faced
- E-Mail Answers
Answer / vicky
1. Perform assay(A1) of undegraded sample say lot x
2. Perform Assay(A2) and RS of Degraded sample of same lot x
3.Calculate mass balance as (A2+Total degradation)/A1*100
Ideally mass balance should be near to 100 but generally it wont be due to factors like non chromophoric impurity production or production of impurities with RRF below 0.8 or above 1.2 etc
| Is This Answer Correct ? | 2 Yes | 0 No |
Which type of column should i use to check the purity of high molecular weight protein using HPLC reverse phase column chromatography? Hi everyone. I wanna to check the purity of high molecular weight protein (collagen) with MW of ~130 kDa using a HPLC. I know C18
0 Answers Petronas, Shanghai Ocean University,
in which situation require to change rs specification?
Why using Holmium oxide in UV calibration
8 Answers Dr Reddys, Matrix, Nakoda Chemicals, Orchid,
why we are performing residue on ignition?
What is the reason of RT change in new column v/s old column in HPLC
What is mean by PDR?
What is cleaning validation of rinse and swabe and its limit with caculation formula.
why deutiriated chloroform used in NMR for sample prepration. what reaction takes place.give reasons
why 2Theta value is consider in the XRPD spectra and how to consider the 2 Theta value
what is the different in Total ash, sulphated ash, acid insoluble ash, alcoholic or non alcoholic ash?
if out of two set of results of moisture analysis first 1 is passing, second one is failing, is it oos ? or vice a versa first 1 is failing and second one is passing. for information mean value to be reported and in mean value the substance is ppassing, is it oos or normaal mean value to be considered?
inhouse product is in capsule form in combination and RLD is in tablet form then can we proceed for multimedia CDP? in inhouse capsule product disso is paddle with sinker in release media is there then RLD product in tablet form then with same as paddle with sinker we can proceed n.a.?
Organic Chemistry 
