What are the differences between GC and HPLC?
Answer / g. subrahmanyam
The difference between HPLC and GC are as follows.
a. In HPLC the mobile phase is a liquid whereas in Gas
Chromatography the mobile phase or carrier is a gas.
b. HPLC is useful for analysis of samples which are
liable to decompose at higher temperatures. GC involves high
temperatures, so compounds are stable at such temperatures.
c. Gas Chromatography is applied for analysis of
volatile compounds whereas non volatile compounds can be
easily analyzed on HPLC
d. Gas Chromatography cannot be used for analysis of
high molecular weight molecules whereas HPLC has
applications for separation and identification of very high
molecular weight compounds
e. HPLC requires higher operating pressures than GC
because liquids require higher pressures than gases for
transport through the system
f. HPLC columns are short and wide in comparison to GC
columns
| Is This Answer Correct ? | 34 Yes | 0 No |
how will you do the prep for unstable componds?
0 Answers AMRI, CTX Life Sciences, Piramal Healthcare,
why xterra column require to use at higher ph?
what is the difference between IR and FTIR instrument analysis
Why potassium dichromate is used in calibration of uv?
What is cleaning validation of rinse and swabe and its limit with caculation formula.
Which type of analysis we have to done uv spectroscopy
what are the standard methods for HPLC?
Defination of ZEEMAN EFFECT in NMR ?
How to calibration of the uv spectroscopy and its test?
if tech transfer fails whay require to do?
What is the exact reason to use THF and IPA in buffers of Reverse phase HPLC as a solvent?
What is similarity factor?