What is difference between Potency & purity
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Answer / krishnamurthy
Purity indicates existence of of required compound rest of
other components(impurities) in a sample matrix.
Potency indicates the strength of required compound rest
of other components(impurities,MC,ROI, OVI,etc) in a sample
matrix. This potency correction is useful for the weight
correction. This gives the exat weight which we taken.
| Is This Answer Correct ? | 15 Yes | 1 No |
Answer / sai
Purity means- it explains how pure our analyte is in the given mixture. It is not related to the how much our analyte is in the given mixture. i.e percentage of our analyte without impurities in HPLC (i.e known or unknown)
Potency means- it is measurement of our analyte how potent it is. i.e purity of our analyte without all possible impurities like chromatographic impurities (HPLC, GC-Residual solvents, TLC), Heavy metals etc..
| Is This Answer Correct ? | 3 Yes | 1 No |
2. Two grams of Benzoic acid are dissolved in 200 ml of water and extracted with 200 ml of diethyl ether. The distribution coefficient of benzoic acid is 100, and its dissociation constant is 6.5 10-5. Calculate the distribution ratio (D) of benzoic acid at pH 2, 5, and 6. 3. Calculate D at pH 2 to 10 (1 unit apart) in the above problem, and plot D versus pH.
Weight balance variation limit during analysis
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Dear Sir, This is Thirunavukkarasu am working in Ordain Health Care AR&D, Am Having one problem While doing method development my question Metadoxine and Pyridoxine same chemical nature and structural activity i tried lot of methods but Analyte eluted same Retantion time i cant separate both peaks. solubility, pH both are same only only difference melting point metadoxine 210 C Pyridoxine 102 C please do the help needful for me