Analytical Chemistry Interview Questions
Questions Answers Views Company eMail

how can you determine a compound acidic or basic?

Celon Labs, Cipla,

2 9679

For LOD and LOQ determination which method is accurate? (slopemethod or s/n ratio method)

Reddy Labs,

4 10103

how to develop the shorter run time for pharmacopeial methods having 100 min run time?

Reddy Labs,

3 9854

How you start the method development of unknown compound.

1 5174

How to determine water content of bis tetrazole amine mono ammonium salt

2963

Is there any difference in principal of reverse phase and normal phase chromatography? and why? Please update. Thank and regard

MSN Pharma,

3 10079

How to use RF and rrf in Rs calculation( either multiply or divide)?

Micro Labs,

4 12068

WHY KBr is used in IR Spectroscopy

GVK,

3 12390

How can you prepare 0.05M Ammonium acetate volumetric solution?

2 22463

Why using 0.5% acetone in methanol mobile phase for HPLC Gradient performance check.

DRL,

2 12113

IF WE INCREASE FLOW RATE RT DECRESE.WHY

2 9662

in hplc calibration injector linearity pass,it means inj and det is good. why to perform detector linearity is it required, if it is required,what is difference between injector and detector linearity in hplc calibration

Dr Reddys, Hetero,

4 13947

how can you decide API molucule acedic or basic compound by test?

Posh Chemicals,

2 9053

acceptance criteria for lod & loq by standard deviation of response and slope??

2086

various methos to calculate precision in validation methods in HPLC?

2 6585


Post New Analytical Chemistry Questions

Un-Answered Questions { Analytical Chemistry }

Please tell me about the pH of Polycaboxylic ether is it in the 5-6 range ever or more than 6

2105


2. Two grams of Benzoic acid are dissolved in 200 ml of water and extracted with 200 ml of diethyl ether. The distribution coefficient of benzoic acid is 100, and its dissociation constant is 6.5 10-5. Calculate the distribution ratio (D) of benzoic acid at pH 2, 5, and 6. 3. Calculate D at pH 2 to 10 (1 unit apart) in the above problem, and plot D versus pH.

1760


in api coa contains only process impurities and in product coa contains degradation impurities?

318


if your product is soluble in 0.1n hcl and water then which you choose as media from these 2 media?

275


all types of questions asked at the cipla interview

4135






some product having water content method with pyridine and ethylene glycol mixture instead of methanol? how they are selecting and methanol is not suitable solvent how ?

2099


could negative ions be produced by bombardment process in mass spectrometry?

1290


on saturation solubility study data how we can find out the bcs class of drug?

358


what is mean by peak intigrity?

337


How to establish relative response factor for hplc. Why it is required?

698


USP methodology, EP methodology, IP methodology, among three if possible to use one methodology for qualify working standard to use USP, EP, IP ? Please explain...

1556


inhouse product is in capsule form in combination and RLD is in tablet form then can we proceed for multimedia CDP? in inhouse capsule product disso is paddle with sinker in release media is there then RLD product in tablet form then with same as paddle with sinker we can proceed n.a.?

289


why we use a particular hplc column for a particular compound give reasons?please

2269


on the basis of bcs class how to proceed the solubility?

278


what are the guidelines for analytical method validations?

591