Is there any difference in principal of reverse phase and normal phase chromatography? and why? Please update. Thank and regard
3 10079in hplc calibration injector linearity pass,it means inj and det is good. why to perform detector linearity is it required, if it is required,what is difference between injector and detector linearity in hplc calibration
4 13947Post New Analytical Chemistry Questions
Please tell me about the pH of Polycaboxylic ether is it in the 5-6 range ever or more than 6
2. Two grams of Benzoic acid are dissolved in 200 ml of water and extracted with 200 ml of diethyl ether. The distribution coefficient of benzoic acid is 100, and its dissociation constant is 6.5 10-5. Calculate the distribution ratio (D) of benzoic acid at pH 2, 5, and 6. 3. Calculate D at pH 2 to 10 (1 unit apart) in the above problem, and plot D versus pH.
in api coa contains only process impurities and in product coa contains degradation impurities?
if your product is soluble in 0.1n hcl and water then which you choose as media from these 2 media?
all types of questions asked at the cipla interview
some product having water content method with pyridine and ethylene glycol mixture instead of methanol? how they are selecting and methanol is not suitable solvent how ?
could negative ions be produced by bombardment process in mass spectrometry?
on saturation solubility study data how we can find out the bcs class of drug?
what is mean by peak intigrity?
How to establish relative response factor for hplc. Why it is required?
USP methodology, EP methodology, IP methodology, among three if possible to use one methodology for qualify working standard to use USP, EP, IP ? Please explain...
inhouse product is in capsule form in combination and RLD is in tablet form then can we proceed for multimedia CDP? in inhouse capsule product disso is paddle with sinker in release media is there then RLD product in tablet form then with same as paddle with sinker we can proceed n.a.?
why we use a particular hplc column for a particular compound give reasons?please
on the basis of bcs class how to proceed the solubility?
what are the guidelines for analytical method validations?