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Analytical Chemistry Interview Questions
Questions Answers Views Company eMail

In BP2013, Loperamid HCl monograph. Assay by titration with 0.1N sodium hydroxide using hydrocloric acid 0.01N and reading the volume added between the 2 points of inflexion. I have a question that if the diluent solvent is ethanol is certainly consumed a amount of volume of titrant, so this volume must be eliminated on the result calculation or not apart from first point which is subtracted above.

3192

If i performing one analysis on C8column then the same analysis done on C18 column then what will happen about Rt;Resulution;Peak shape Explain ?

1 8189

what is peak purity? how may types of methods to determine peak purity?

Mylan,

3 14879

why using Potentometry What Purpose? differance between manual and potentiometry? why using Some of materials in usig potentiometry? What is use of mericuric acetate in Potentiometry

Biocon,

1 5821

iam using ph instrument lab india make.3ponit and 5point.in calibration time 3point slope will come 98.89and 96.87.that limit is 85 to 105.what basis slope will come.any calucalation between them.5point wiicome slope 99.89?why 3p0int came 2 values

1 5506

iam usig ph buffers merk. manually how to prepare ?

2329

Sulphated Ash incresed it will effect on product yield?

Biocon, Lupin,

3 6081

in loss on drying Why follows on constant weight not more than 0.5 mg, any region

Biocon,

1 14702

difference between selectivity and specificity

Troikaa Pharmaceuticals,

2 13308

when we talk about change in entropy we consider total entropy means of surround +entropy of system but when we talk about change in Gibss free energy we consider entropy of system.explain with reason.

ABC,

2099

differnc btw c18 and c-8 column

Cipla,

3 13485

use of stry light

1 7620

when we have polar type of sample and solvnt hen which type of stationry phase we have to use

3 7770

what is motor rotation in case of sucrose

1 4678

why equlirium conatant of water have 14 value

GVK Biosciences,

1 3303


Post New Analytical Chemistry Questions

Un-Answered Questions { Analytical Chemistry }

If vendor having more imp than monograph then how to proceed? and how to set spec?

1006


How much is the standard area for glc analysis

2334


Is it nessesary all multimedia dissolution require descriminatory?

861


How they found 1mL of K.F reagent is equivalent to 5mg of water and if we change the composition of K.F reagent, is it can neutralize more amount of water?

1830


In HPLC calibration, caffeine is used as primary standard for wave length calibration due to caffeine is having dual maxima at 273 & 205 nm and one minima at 245 nm. Any body can give reference of these details from any pharmacopeia (with chapter no.) or any other authentic guideline?

2017


why should we perform dissolution PVT calibration only by UV spectrometer, not by HPLC ?

1755


In performance Check of GC Why Hexadecane Peak is Considered 

3107


why we use Dichlorobenzene.nitrobezine.t-butyldi sulhate.for calibration of gc Head space

2334


What is the diffrence in japan mkt requirement in analytical method validation over US?

773


if your impurity coeluting with each other in that situation how require to set specification? is it acceptable?

1049


how to calculate elemental impurities?

1086


What is rs test why we are performing rs test?

1908


In GC calibration,what is the procedure to calibrate the TCD (thermal counductivity detector)suggest ?

3226


What is column in chromatography?

2293


What is the formula for relative diffrence for standard solution in solution stability in validation?

863