1)why use benzophenon,uracil in hplc calibration. 2)why use sucrose in polarimeter calibration. 3)what is S/N ratio, noise and drift in hplc 4)how we can find lod and loq in method validation
1 149631 why polyesterene film used for ftir calibration ? 2 why k2cr2o7 is used for control of abs in uv ? 3 why holmium oxide used for control of wavelength in uv
3 13063In lcms analysis some times we get sodium and potassium adducts. if the compound is havine sodium ions how can we confirm wether sodium is from sample or it is a adduct?
2 7752Post New Analytical Chemistry Questions
about method developement in hplc
How to decide assay range for non pharmacopeial API analysis by HPLC? Could you give me any reference for same e.g Guidelines or Paper publications?
what is lod and loq ?,why use k2cr2o7 , kcl h2so4 in uv calibration ?,why use benzophenone & caffene acetone in hplc calibration ?,what is leading peak in hplc ?why we do the calibration of limit of stry light in hplc & uv ?
What should be the level/ Percentage of Arsenic in Arsenic free zinc.
If change in specification which parameter require to do for validation? if change in chromtographic condition then which parameter? if api change then which parameter? if change composition then which parameter? if old method not work out then whicj parameter? if additional one impurity added then which parameter of validation require to do on above each conditions? elaborate separately
how a particular wavelength can be different for a particular compund while analysing by uv and by HPLC.
in which situation ion pair require to use?
Why acetonitrile and water are used as extraction solvent when analysis melamine? I thought they are miscible and won't be able to separate...
Why irmoisture balance is used for corrugated box moisture testing
why we use glass fiber filters use in some situation?
how require to interprit the method precision data of hptlc?
how you confirm the assay method?
which are the sizes of capsules?
Why potassium dichromate is used in calibration of uv?
what is mean by dissolution biowaiver study?