s.ramu


{ City } hyd
< Country > india
* Profession * exceutive
User No # 107668
Total Questions Posted # 10
Total Answers Posted # 7

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Questions / { s.ramu }
Questions Answers Category Views Company eMail

what is definition of validation? which components are followed give detail?

 Analytical Chemistry 1929

What is the principal of particle size analyzer?brief explain instrumentation?

Pharmaceutical,

Lab Technicians 2029

How to calculate lamp energy in hplc?

 1 Analytical Chemistry 3389

Definition of beers_ lamberts law

Aarti Industries, Agio Pharmaceuticals, Emcure, Supriya Lifescience,

4 Analytical Chemistry 6970

Why monograph of hplc coming upperside of drift but in IR monograph coming in drift side?

 1 Analytical Chemistry 3474

WHY given much noise PDA dector then VWD Dector

 Analytical Chemistry 1590

Data was integrated with RRT CONCEPT OR Overlay with SSTchrmatogram concept which is better?

 1 Analytical Chemistry 2441

How to define samples weight in moisture content

 1 Analytical Chemistry 1880

In the HPLC Calibration done wavelength accuracy done between 200nm-280nm .but not done remaining 300-400nm not done ?

 Analytical Chemistry 565

in hplc chromatogram started from left to right and in uv spectrum started from left to right

 Analytical Chemistry 548



Answers / { s.ramu }

Question { 7697 }

why potassium dicromate use in calibration of UV VIIBLE
SPECTROCOPY ?


Answer

potassium dicromate having 570-620nm and uvhigest wavelength is600 so we can use that

Is This Answer Correct ?    2 Yes 0 No

Question { NCL, 5289 }

How to study genotoxicity of impurities in API?


Answer

study genotoxicity of impurities in API based drug dosage

Is This Answer Correct ?    0 Yes 1 No


Question { 4911 }

Why we use methy Ethyl Propylparabine For HPLC Calibration


Answer

Ethyl Propyl, and methyl parabines are stongly gives reputability results.so we can use.

Is This Answer Correct ?    1 Yes 0 No

Question { GVK, 20189 }

Why we inject a standard 6 times for Related substances by
HPLC and 5 times for Assay?


Answer

In Related substance by we inject standard prepared 6times for repeatability results as usp guidelines.
in assay analysis 5times for RSD,STDdev.and we inject stndard inj for Calulation for batches assay. inassay analysis we are also inject 6injectios.
in rs analysis standard 6prepns.

Is This Answer Correct ?    2 Yes 4 No

Question { GVK, 20189 }

Why we inject a standard 6 times for Related substances by
HPLC and 5 times for Assay?


Answer

In R.S by HPLC We inject 6preprations,as for ICH guide lines
in validations we prepare system precisson,intermediate precisson, method pression as6preparations.we based to this ich guideline supported data we inject 6preparations.

Those technical supotred data (6inj) show repatabulity results.

Is This Answer Correct ?    0 Yes 3 No

Question { IPCA, 19721 }

who is the father of HPLC?


Answer

Father of chromatography was Mikhail tswett ,Father of HPLC casaba harwarth

Is This Answer Correct ?    7 Yes 1 No

Question { Micro Labs, 12528 }

How to use RF and rrf in Rs calculation(
either multiply or divide)?


Answer

RRF= Impurity area/standard area.
RF= 1/RRF

Is This Answer Correct ?    1 Yes 8 No