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Why and when RRF is required to be known in RS Method? How is it helpful during method development?
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Answer / bandari
To Identify the impurity and exact value of result of particular impurity
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Answer / avtar singh
Relative response factor is to determine the impurity quantitatively for a the very precise method of Related substance......RRF is a ratio of response factor of impurity vs response factor of API ..
RF=area of peak/ conc. in mg/ml......
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Answer / rambabu vattikuti
In RS methodology RRF values establish for below points purpose
1) cost reduce purpose every time impurities not required for analysis and non availability of impurities use
2) RRF Values required for quantitative calculation and reporting purpose.
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