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What is the limit for friability of tablets?
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Friability test is used to determine the physical strength
or tablet breaking force for compressed, uncoated tablets.
Tablet Friability Apparatus is used for the test. Remove
any loose dust from the tablets and accurately weigh 10
tablets. They are placed in the drum which rotates at 25±1
rpm. Rotate the drum 100 times, and remove the tablets.
The sample fails the test, if any of the 10 tablets
cracked, cleaved, or broken is present. If the weight loss
is more than 1.0%, the test is repeated for twice and the
mean of three tests is calculated. The mean not more than
1.0% is considered acceptable.
Please note that for Effervescent tablets and chewable
tablets the friability limits may differ.
| Is This Answer Correct ? | 106 Yes | 8 No |
Answer / s.k.afridi
Friability test is used to determine the physical strength
or tablet breaking force for compressed, uncoated tablets.
Tablet Friability Apparatus is used for the test. Remove
any loose dust from the tablets and accurately weigh 10
tablets or weight of the sample NLT 7 gm for small tablets. They are placed in the drum which rotates at 25±1
rpm. Rotate the drum 100 times, and remove the tablets.
The sample fails the test, if any of the 10 tablets
cracked, cleaved, or broken is present. If the weight loss
is more than 1.0%, the test is repeated for twice and the
mean of three tests is calculated. The mean not more than
1.0% is considered acceptable.
Please note that for Effervescent tablets and chewable
tablets the friability limits may differ.
| Is This Answer Correct ? | 15 Yes | 0 No |
Answer / aimsizer
Friability test limits is that if obviously cracked, cleaved, or broken tablets are present in the tablet sample after tumbling, the sample fails the test. If the results are doubtful or if the weight loss is greater than the targeted value, the test should be repeated twice and the mean of the three tests determined. A maximum mean weight loss from the three samples of not more than 1.0% is considered acceptable for most products. Conventional compressed tablets that lose less than 0.5% to 1% of weight are considered acceptable, less than 0.5% shows superior friability of tablets.
| Is This Answer Correct ? | 4 Yes | 4 No |
Answer / md munim rahman
Why chewbale Tablets Frability test fail...
| Is This Answer Correct ? | 0 Yes | 0 No |
Answer / suhel patel
Hii Frnds,
physical strength
or tablet breaking force for compressed, uncoated tablets.
Tablet Friability Apparatus is used for the test. Remove
any loose dust from the tablets and accurately weigh 10
tablets. They are placed in the drum which rotates at 25±1
rpm. Rotate the drum 100 times, and remove the tablets.
The sample fails the test, if any of the 10 tablets
cracked, cleaved, or broken is present. If the weight loss
is more than 1.0%, the test is repeated for twice and the
mean of three tests is calculated. The mean not more than
1.0% is considered acceptable.
| Is This Answer Correct ? | 0 Yes | 0 No |
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