Interested to Buy Any Domain ? << Click Here >> for more details...
What is the limit for friability of tablets?
- 10 Answers
- 57382 Views
- Glenmark, I also Faced
- E-Mail Answers
Answers were Sorted based on User's Feedback
Friability test is used to determine the physical strength
or tablet breaking force for compressed, uncoated tablets.
Tablet Friability Apparatus is used for the test. Remove
any loose dust from the tablets and accurately weigh 10
tablets. They are placed in the drum which rotates at 25±1
rpm. Rotate the drum 100 times, and remove the tablets.
The sample fails the test, if any of the 10 tablets
cracked, cleaved, or broken is present. If the weight loss
is more than 1.0%, the test is repeated for twice and the
mean of three tests is calculated. The mean not more than
1.0% is considered acceptable.
Please note that for Effervescent tablets and chewable
tablets the friability limits may differ.
| Is This Answer Correct ? | 106 Yes | 8 No |
Answer / s.k.afridi
Friability test is used to determine the physical strength
or tablet breaking force for compressed, uncoated tablets.
Tablet Friability Apparatus is used for the test. Remove
any loose dust from the tablets and accurately weigh 10
tablets or weight of the sample NLT 7 gm for small tablets. They are placed in the drum which rotates at 25±1
rpm. Rotate the drum 100 times, and remove the tablets.
The sample fails the test, if any of the 10 tablets
cracked, cleaved, or broken is present. If the weight loss
is more than 1.0%, the test is repeated for twice and the
mean of three tests is calculated. The mean not more than
1.0% is considered acceptable.
Please note that for Effervescent tablets and chewable
tablets the friability limits may differ.
| Is This Answer Correct ? | 15 Yes | 0 No |
Answer / aimsizer
Friability test limits is that if obviously cracked, cleaved, or broken tablets are present in the tablet sample after tumbling, the sample fails the test. If the results are doubtful or if the weight loss is greater than the targeted value, the test should be repeated twice and the mean of the three tests determined. A maximum mean weight loss from the three samples of not more than 1.0% is considered acceptable for most products. Conventional compressed tablets that lose less than 0.5% to 1% of weight are considered acceptable, less than 0.5% shows superior friability of tablets.
| Is This Answer Correct ? | 4 Yes | 4 No |
Answer / md munim rahman
Why chewbale Tablets Frability test fail...
| Is This Answer Correct ? | 0 Yes | 0 No |
Answer / suhel patel
Hii Frnds,
physical strength
or tablet breaking force for compressed, uncoated tablets.
Tablet Friability Apparatus is used for the test. Remove
any loose dust from the tablets and accurately weigh 10
tablets. They are placed in the drum which rotates at 25±1
rpm. Rotate the drum 100 times, and remove the tablets.
The sample fails the test, if any of the 10 tablets
cracked, cleaved, or broken is present. If the weight loss
is more than 1.0%, the test is repeated for twice and the
mean of three tests is calculated. The mean not more than
1.0% is considered acceptable.
| Is This Answer Correct ? | 0 Yes | 0 No |
WHEN WILL GUJRAT GOVERNMENT ANNOUNCES DRUG INSPECTOR POSTS AND WHEN WILL BE THE EXAM CONDUCTED? INFORM ME AND ALSO EAMINATION DATE
Why we use pyrene in HPLC calibration ( UV-vis/PDA)
2 Answers Lupin, MSN, MSN Pharma,
Why Assay and CU test performed differently?
how to select HPLC column for a particular product
why u want to join as a m.r?
define the starting material?
what is difference between uniformity of content and content uniformity as official test for tablet
what are the role of medical reperstative
What should be the minimum limit of a working standard?
which std you used for chemical calibration in dissolution?
what does in simple words meant by thermodynamically stable means??
what are the most common infectious diseases a pharmacist sees? Do pharmacists routinly encounter antibiotic resistent in some of the infectious agents that patients have contacted? if so which onces?
Pharmacy 
