calculations of LOD & LOQ

Question Posted / audumbar

4 Answers
13993 Views
Dr Reddys, I also Faced
E-Mail Answers

Answers were Sorted based on User's Feedback

calculations of LOD & LOQ..

Answer / murugesan

LOD : signal to noise ratio 3;1
LOQ : signal to noise ratio 10;1

Is This Answer Correct ?

25 Yes

3 No

calculations of LOD & LOQ..

Answer / supriya

LOD: Limit of detection -It should be between 3-10
(by S/N ratio method)

LOQ: Limit of Quantification -It should be between 10-30
(by S/N ratio method)

Is This Answer Correct ?

9 Yes

1 No

calculations of LOD & LOQ..

Answer / phanindra

LOD: signal to noise ratio 3Or2:1

LOQ : signal to noise ratio 10:1

According to ICH Q2B

Is This Answer Correct ?

5 Yes

1 No

calculations of LOD & LOQ..

Answer / omkar singh yadav

LOD is 3-10 by siganal to noise ratio.
LOQ is 10-30 by siganal to noise raito

LOD = 10*Standard deviation/ slope of calibration curve

LOQ = 3.3*standard devition/ slope of calibrtion curve

Standard devation is calculating in many ways.
in Simple Linerity curve it is also called Styrex.

For Japan market is calclted as Standard error and slope
is calculated as X-variable.

There are so many ways to calculate the LOQ and LOD

Is This Answer Correct ?

4 Yes

2 No

Post New Answer