Analytical Chemistry Interview Questions, Answers for Freshers and Experienced asked in various Company Job Interviews

Analytical Chemistry Interview Questions

Questions Answers Views Company eMail

please explian me about area normalisation method,diluted standard method,impurity vs impurity and which one has to be selected in method development

Pfizer,

1628

How they found 1mL of K.F reagent is equivalent to 5mg of water and if we change the composition of K.F reagent, is it can neutralize more amount of water?

1778

How can we calculate offset value pH measurment

Dr Reddys,

1510

What is stray light in uv what are units for stray light

Dr Reddys,

1652

Colorimtry

Dr Reddys,

1658

What are usp limits for theoritical plats,resoution,tailing factor,peak to valley ratio

Dr Reddys,

1898

What are usp limits for total impurities,unknown impurity

Dr Reddys,

1 3678

how to get accurate result for Residue on evaporation in purified water

1647

Why acetonitrile and water are used as extraction solvent when analysis melamine? I thought they are miscible and won't be able to separate...

1689

In HPLC calibration, caffeine is used as primary standard for wave length calibration due to caffeine is having dual maxima at 273 & 205 nm and one minima at 245 nm. Any body can give reference of these details from any pharmacopeia (with chapter no.) or any other authentic guideline?

1973

could negative ions be produced by bombardment process in mass spectrometry?

1781

A ha tc is actual defination of retention time?

1617

How to check hplc detecter sensitivity?

Gland Pharma,

1 2285

(0.41)d what is d?

Gland Pharma,

1 2845

How to estimate potassium?

1 2142

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Un-Answered Questions { Analytical Chemistry }

please explian me about area normalisation method,diluted standard method,impurity vs impurity and which one has to be selected in method development

1628

if tech transfer fails whay require to do?

845

If suppose 10 methods of dissolution given in pharmacopoeial for single content product then which method out of 10? or all 10 require to follow?

986

in api coa contains only process impurities and in product coa contains degradation impurities?

701

process of Diclofenac sodium,IP.

2211

how to develop the icp ms method? Application of icp ms?

811

Ratio of Water and Acetonitrile(diluent) is not recommended to use in cleaning method validation,why?

2963

Qc interview questions

1741

Which type of column should i use to check the purity of high molecular weight protein using HPLC reverse phase column chromatography? Hi everyone. I wanna to check the purity of high molecular weight protein (collagen) with MW of ~130 kDa using a HPLC. I know C18

1915

please explain about aluminium hydroxide assay

1132

for inorganic molecules require to do RS, Assay and disso?

733

what is procedure of actual procedure for registration of drug?

2012

[3/30, 13:29] Manoj P Venkatpurwar: How hplc column selection according to structure? How mobile phase buffer selection on molecule structure?

791

what is the importance of peak purity in HPLC and how we can calculate through manul(not software)?

4488

How can the GC or HPLC method is selected to determine the impurity profile in drug product?

7596

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