Analytical Chemistry Interview Questions, Answers for Freshers and Experienced asked in various Company Job Interviews

Analytical Chemistry Interview Questions

Questions Answers Views Company eMail

What is the principle of GC/HPLC ?

BioCan, Biocon, Megafine Pharma,

4 57424

Why pH Range has been fixed as 0 to 14 ?

Akums, Cipla, Matrix, SUN,

1 7414

How you develop a method in HPLC?

CU, Perrigo, Wockhardt,

2586

why using buffers in hplc inteed of water

5 14323

How long we can use hygroscopic reference standard in terms of water absorb.I mean in line with respective monograph's specification or more than that?

1 3095

Why we use methy Ethyl Propylparabine For HPLC Calibration

1 5472

What is use of LOD and LOQ in validtion and give range and in calculation why we use 3.3* LOD here why we use 3.3

Dr Reddys, IPCA, Reddy Labs,

2 6757

In specificity what parametrs are consider why that parametrs

2 6909

ash or residue in that what will be there.

3 6581

How can we determine Moisture content of HI?

Cipla, Reddy Labs,

1 3384

What is difference between oos

Gennex,

7 28026

what is the differance between Analytical and semi micro balance?

2 13755

In the method validation proceedure,lod & loq calculation we use the formulae for LOD=3.3*SD/slope and for LOQ=10*SD/slope,why we use 3.3 & 10 in the formulae?

1 10962

In HPLC Chromatographic separation Resolution equation is Rs = 1.18 (tR2 –tR1)/wh1+Wh2, Where, tR2 and tR1 is run time of eluent ratios of the distances from the point of application to the centers of the spots and the distance travelled by the solvent front from the point of application (retardation factor), and Wh1and Wh2 , is peak width of at half height. What is 1.18 ?

1 7218

what is mean by theoritical plates(not formula) ?

Micro Labs,

4 14713

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Un-Answered Questions { Analytical Chemistry }

What is split ratio in Gc? Splitless? how requirr to select?

849

How do we fix the sample concentaryion in hplc method development?

1115

if you get peak in blank then what require to do?

925

iam usig ph buffers merk. manually how to prepare ?

2242

if your impurity coeluting with each other in that situation how require to set specification? is it acceptable?

931

What is the difference between Discriminating media and DPDM(Dissolution Profile with Different Media)

7501

[3/30, 13:29] Manoj P Venkatpurwar: How hplc column selection according to structure? How mobile phase buffer selection on molecule structure?

729

What is the principle of HPLC, GC, LCMS, GCMS,LC QQQ, GC QQQ, LC Q TOF and GC Q TOF. What are the applications and Specificity?

8840

WHY pKa value is more important than pH value of the mobile phase in HPLC?

1740

Please give idea about method development for cleaning method and how maco level establish

713

CAN WE DETERMINE THE PEAK PURITY IN GAS CHROMATOGRAPHY ANALYSIS?

1170

Did anybody have method for acetyl cysteine effervescnce tablet

2220

which batch require to use for analytical method validation?

764

analytical method validation require to with respect to release specification or shelf life specification?

755

WHAT IS THE CRITERIA FOR SELECTION OF TIME OF DISSOLUTION AND THE MEDIUM OF DISSOLUTION?

2539

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