Bio Informatics Interview Questions
Questions Answers Views Company eMail

How will you value a biotech company as opposed to a consumer products company?

591

How did you get into the field of bioinformatics?

533

Have the proteins of a family generally acquired distinctive properties within each of these three kingdoms for ancient families that arose before bacteria, archaea and eukaryotes diverged?

627

Does multidrug resistance (mdr) arise by activation of stable genes encoding drug efflux pumps or by mutations of genes encoding other types of transporters in bacterial pathogens?

648


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Un-Answered Questions { Bio Informatics }

What is the idea behind ?weighting? sequences in the package CLUSTAL W for multiple alignment? How are these weights calculated?

1544


Bootstrap analysis evaluates evolutionary trees by sampling columns from the original alignment with replacement (multiplying or removing some of them) and computing a proportion of times that a particular branch appears in the resulting trees. What is the main idea behind this approach?

1702


How to Count number of nucleotide substitutions ?

1794


What is a homologue?

1783


What is the science of bioinformatics?

616






Draw the E-R diagram for the database of a departmental store having the following relational database scheme Employees(e-no, address) Department(d-name) work-n(e-no, d-name) Looking-after(d-name, e-no) Item (item-no, brand-name, model-no, cost-price, sale-price)

12421


Explain about needleman-wunsch algorithm?

1794


How to identify common acc.numbers from among a set of files ?

2339


How do ESTs work?

1520


How to caculate coordinates of each atoms on 3 D HP model?

1697


How to run DOCK 6 using cygwin?

5833


Did bacteria, archaea, and eukaryotes exchange transporter genes appreciably during the past two billion years?

661


Suppose the Blast search returned 100 hits. Of these, 17 were false positives and we knew that there were 165 sequences in the database which should have returned a hit with our sequence. How many false negatives were there, and what is the sensitivity and selectivity of Blast in this instance?

1850


What are the bioinformatic tools applied to micromolecular evolution?

589


How do you find the most recent human sequence data in the data bases inorder to determine physical maps?

1613