s.narayana


{ City } hyderabad
< Country > india
* Profession * dy.manager-qc
User No # 42024
Total Questions Posted # 0
Total Answers Posted # 7

Total Answers Posted for My Questions # 0
Total Views for My Questions # 0

Users Marked my Answers as Correct # 85
Users Marked my Answers as Wrong # 18
Questions / { s.narayana }
Questions Answers Category Views Company eMail




Answers / { s.narayana }

Question { Reddy Labs, 30132 }

why we use only vanilline , acetanilide,& caffeine For the
Calibration of melting point appartus?


Answer

vanilline - 81°C to 83°C (range-1.5°)
Acetanilide - 164°C to 165.7°C (range-1.0°)
Caffeine - 235.6°C to 237.5°C (range-1.0°)
All three standards starting & Ending points is within 1.5°
only.
In our operational way also it covers minimum, middle &
Maximum calibration covered.

Is This Answer Correct ?    19 Yes 4 No

Question { Cipla, 14932 }

on what basis SOP's can be changed? IF mobile phase ratio
is 70:30 to how much % can we change the ratio in HPLC
process


Answer

I agree with Dr.SP. Goswami. 10% mobile phase ratio can be
changed, same thing you justify in AMV- ruggedness
parameter.After justification only you revise your MOA as
per your change.

Is This Answer Correct ?    5 Yes 0 No


Question { Medreich, 23730 }

Why do we use 0.005M h2so4 solution for preparation of
k2cr2o7 solution for UV calibration?


Answer

K2cr2o7 is freely soluble in 0.005M Sulphuric Acid.

Is This Answer Correct ?    23 Yes 6 No

Question { Biocon, 25564 }

is there any material other than caffene to calibrate hplc
detector


Answer

We Can use Erbium Perchlorate also, the maxima is 379 plus
or minu 2nm.

Is This Answer Correct ?    11 Yes 3 No

Question { 10799 }

what is range of Vivible UV ? What is UV& Vivible
spctroscopy use for ?


Answer

UV Region is 190 - 380nm
Visible Region is 380 - 780 nm

Is This Answer Correct ?    7 Yes 3 No

Question { 417691 }

1 % solution is equal to how much ppm


Answer

1% solution is euivalent to 10000 ppm (Parts per million).

Calculation: 1.0gm / 100 ml = 1%

1.0gm / 100 ml X 1000000 = 10000 ppm

Is This Answer Correct ?    2 Yes 0 No

Question { Reddy Labs, 23977 }

What is the Deference between Bulk density & Tap density ?


Answer

Bulk Density (0 taps or Untapped): As is volume in
g/ml.This is called as apparent volume.

Tapped Density: after tapping only we can measure the qty
as g/ml. As per USP two types of methods is there, Method-
I&II.
Based on the powder nature tapping are fixed.500 taps, 750
taps & 1250 taps.(Varience% is NMT 2%)
Naturally all powder grades are fixed in 1250 taps.

After 1250taps also varience is more, then go to USP-II
method or any customer requirement is there then we can use
Method-II.

Is This Answer Correct ?    18 Yes 2 No