What are Beta-lactams?
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Answer / guest
A beta-lactam ring (β-lactam) or penam is a lactam with a
heteroatomic ring structure, consisting of three carbon
atoms and one nitrogen atomA beta-lactam ring (β-lactam) or
penam is a lactam with a heteroatomic ring structure,
consisting of three carbon atoms and one nitrogen atomA
beta-lactam ring (β-lactam) or penam is a lactam with a
heteroatomic ring structure, consisting of three carbon
atoms and one nitrogen atom
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Answer / rajasekhar
These are crucial enzymes in the cross-linking of
peptidoglycan .
The basic building block of the cell wall
act as a false substrate for D-alanyl-D-alanyl
transpeptidases requires carboxylate or sulfonate group of
beta-lactam to react the a serine residue of
transpeptidases to give an inactive acylated enzyme
transpeptidases are located in periplasmic space.
They are capable of hydrolysing penicillins, broad-spectrum
cephalosporins and monobactams. Often associated with
resistance to aminoglycosides and fluoroquinolones .
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