Interested to Buy Any Domain ? << Click Here >> for more details...
how do you established the RRF for unknown impurity
- 6 Answers
- 13131 Views
- Square Pharma, I also Faced
- E-Mail Answers
Answer Posted / pramod br
Relative Response Factor (RRF) is an analytical parameter used in chromatographic procedures to control impurities/degradants in drug substance and drug product.
RRF is used to correct the difference in detector response of impurities with analyte peak. RRF is established by the slope method with linear range of solutions (usually +/-50% of the specification level).
RRF= Slope of impurity / Slope of analyte.
| Is This Answer Correct ? | 0 Yes | 0 No |
Post New Answer View All Answers
can i use hplc detector to uplc and why?
from where i get mortar pastle for glass bottle crush? it's required for testing of it?
if you get peak in blank then what require to do?
why should we perform dissolution PVT calibration only by UV spectrometer, not by HPLC ?
In performance Check of GC Why Hexadecane Peak is Considered
Why acetonitrile and water are used as extraction solvent when analysis melamine? I thought they are miscible and won't be able to separate...
what is mean by dissolution biowaiver study?
why glutent are detected in the rice cereal baby food product even manufacturer claimed that they are using rice and milk only?we have using ELISA to do the test,and rice supposed not containing any glutent,rite?We already repeat the test so many times and it still detected.just wondering where the glutent came from?
Ph meter can show more than 14 ph reading? Why ph range in between 1 to 14 only?
Why Ethanol is Used for Standardization of GC Head space?
What is importance of pH in the Heavy metal test and How it effect on the test results?
how much mass should be there in volumetric flask while in preparation of sample for assay?
1)What's the meaning of Absorption,give a example. 2)What's the meaning of Adsorption,give a example. 2)what is the difference between Absorption and Adsorption.
all types of questions asked at the cipla interview
How to set analyticl specification for combination products?
