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Answer Posted / dr. nalla kumar ponnuswamy
GC-HS is useful for Residual solvents. Since the sample is heated about 40 minutes. Then the volatiles present in the sample will come to the empty space (Head space) of the vial. Then the needle will suck the vapour and inject into GC. It means we are extracting the volatiles from the material before injection.
GC and GC-HS both are used for residual solvents in by GC we measured for volatile solvents in this direct inject the sample into the column and in GC-HS is also used for volatile solvents in this we apply the pressure to inject the solvent as vapour into the column and both r used for non-volatile solvents there are converted into volatile solvents.
Useful for finding % purity and impurity profile of Petroleum Hydrocarbon, Flavours, Drugs, Pesticides and solvents. Analysis of gaseous sample. Detection of residual chlorinated compounds. Detection of trace level of solvents in drugs. Detection of volatile organic content in drugs, dyes, carbohydrates and polymers etc. by GC-HS.
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