Interested to Buy Any Domain ? << Click Here >> for more details...
How to choose concentration of LOQ solutions for RS analysis? Example.
- 1 Answers
- 3487 Views
- Abbott, Indoco Remedies, I also Faced
- E-Mail Answers
Answer Posted / sachin patil
Its depend on your test concentration and the specification limit, means if specify limit is 1.0% in quality and in control have 0.5% then your LOQ concentration must be below the 50% of your specify limit of of control and % RSD of recovery at this LOQ level must be performed and should be pass.
| Is This Answer Correct ? | 0 Yes | 0 No |
Post New Answer View All Answers
How require to perform linearity as per ANVISA? What are the acceptance criteria?
How would you decide dissolution medium for NCE compound of class I drug
Loss of linearity in tkn analysis, possible reasons?
What is a difference between potency and purity?
How to establish relative response factor for hplc. Why it is required?
iam usig ph buffers merk. manually how to prepare ?
What are modes of quantification in related substances
what is the disso medium for tropsiun chloride
for inorganic molecules require to do RS, Assay and disso?
how a particular wavelength can be different for a particular compund while analysing by uv and by HPLC.
HI,I CLEARED BOB CLERK EXAM. MY INTERVIEW WILL BE ON 9TH OCTOBER,2010.PLEASE SEND ME INTERVIEW QUESTIONS AND ANSWERS. THANK YOU.
How can I develope method of dissolution by HPLC OR UV
2. Two grams of Benzoic acid are dissolved in 200 ml of water and extracted with 200 ml of diethyl ether. The distribution coefficient of benzoic acid is 100, and its dissociation constant is 6.5 10-5. Calculate the distribution ratio (D) of benzoic acid at pH 2, 5, and 6. 3. Calculate D at pH 2 to 10 (1 unit apart) in the above problem, and plot D versus pH.
If change in specification which parameter require to do for validation? if change in chromtographic condition then which parameter? if api change then which parameter? if change composition then which parameter? if old method not work out then whicj parameter? if additional one impurity added then which parameter of validation require to do on above each conditions? elaborate separately
