What are the class-1 residual solvents listed in ICH guidelines?
Answer Posted / b.gangatharan
According to Q3c in ICH guidelines and USP Chapter <467> the following 4 solvents are listed .
1)Benzene
2)1,2-Dichloro ethane
3)1,1-Dichloroethene
4)1,1,1-Trichloroethane
Thanks,
B.Gangatharan
Caplin point Ltd,unit-1
| Is This Answer Correct ? | 4 Yes | 3 No |
Post New Answer View All Answers
what you do when compound having dwel wavelength?
In IR spectra, generally a molecule vibrates without apply emr or ir light?
how require to select dissolution media? what is discrimination?
in dissolution if one bowl got 70 percent 2nd bowl got 80 percent and 3rd bowl got 90 percent then how proceed?
mahagenco syllabus for the post of chemist
some product having water content method with pyridine and ethylene glycol mixture instead of methanol? how they are selecting and methanol is not suitable solvent how ?
why sre you used Potassium hydrogen phthalate in standarisation of 1N NaOH and 0.1 N Perchloric Acid?
How require to develop GC method? how to select diluent, GAS, column selection and other chromatographic conditions?
why require to add enzymes in capsules dissolution only? is it require to tablet also?
In HPLC (Waters) software Empower1,2 &3 what is the updation for each version
For titration in anhydrous media with perchloric acide, if lack of titrator, Which indicator is been used for replacement. How calculate pH of test solution to choose suitable indicator?
why require the ph, buffer during hplc mobile phase?
calibrtion procedue of LC-MS
why digestion require in icpms?
How can we calculate offset value pH measurment