why KF factor is between 4.5 to 7.5 mg/ml ? why ? why
sometime pyridine is used in analysis like in raw material
solvent like acetone etc?
Answer Posted / nagulmeera
Acetone is highly reactive, so it reacts with methanol to give side products as water and ketals, our aim is to find water content but here excess water is generated so the titre value is not tru
| Is This Answer Correct ? | 6 Yes | 1 No |
Post New Answer View All Answers
AT WHAT CONDITIONS WILL YOU ANALYSE A SAMPLE,WHICH ARE PRESERVED AT OTHER THAN THE AMBIENT CONDITIONS?(ie COLD STORAGE SAMPLES BELOW 20* CENTIGRADE?
If change in specification which parameter require to do for validation? if change in chromtographic condition then which parameter? if api change then which parameter? if change composition then which parameter? if old method not work out then whicj parameter? if additional one impurity added then which parameter of validation require to do on above each conditions? elaborate separately
How to establish relative response factor for hplc. Why it is required?
can we use the same detector in HPLC as well GC and what could be the differences we can find in the final chromato graph in any aspects?
How to calculation of residual solvent methanol (3000 ppm) standard solution, and how many quantity used of test sample
if content uniformity passing but dissolution varrying then what is next step?
How do we quantify crystaline and amarpous forms by using (NMR, XRD)spectroscopic techniques? Which any others instruments are useful for this quantification? explain
how you start RS method development when for new product?
What is control room temperature and which guide line says?
USP methodology, EP methodology, IP methodology, among three if possible to use one methodology for qualify working standard to use USP, EP, IP ? Please explain...
how to set sample and standard concentration in RS method?
WHICH STANDARD WE USE IN SILICA ANALYSIS IN SILICA-GEL METHOD FOR SOLID SAMPLE
How do we fix the sample concentaryion in hplc method development?
how to calibrate hplc & gc
Related substance method equivalency on control sample or spiked sample?